Tabernanthe iboga Health effects and herbal facts

Known as
bitter-grass eboka iboga ibogo leaf-of-God sacredwood

Tabernanthe iboga or simply iboga is a perennial rainforest shrub and psychedelic, native to western Central Africa. Iboga stimulates the central nervous system when taken in small doses and induces visions in larger doses. In parts of Africa where the plant grows the bark of the root is chewed for various pharmacological or ritualistic purposes. Ibogaine, the active alkaloid, is also used to treat substance abuse disorders and depression. A small amount of ibogaine, along with precursors of ibogaine are found in Voacanga africana. Normally growing to a height of 2 m, T. iboga may eventually grow into a small tree up to 10 m tall, given the right conditions. It has small green leaves. Its flowers are white and pink, while the fruit can be either an elongated oval shape, or a round spherical shape, both having an orange colour. Its yellow-coloured roots contain a number of indole alkaloids, most notably ibogaine, which is found in the highest concentration in the root-bark. The root material, bitter in taste, causes an anaesthetic sensation in the mouth as well as systemic numbness to the skin.

Tabernanthe iboga

Medical use

Economic importance of Tabernanthe iboga

Medicines folklore source of ibogaine
Social halucinogen religious/secular

Gallery

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Geografical distribution

  • AFRICA
    Native
    • East Tropical Africa: Tanzania
    • West-Central Tropical Africa: Central African Republic; Congo; Equatorial Guinea; Gabon; Zaire
    • South Tropical Africa: Angola
    Cultivated
    • West Tropical Africa: Cote D'Ivoire
  • ASIA-TROPICAL
    Native
    • Indo-China: Cambodia

Biological activities

Anthelmintic
Tannin found in Root
AntiHIV
Tannin found in Root
Antibacterial
Tannin found in Root
Anticancer
Tannin found in Root
Anticariogenic
Tannin found in Root
Anticholinesterase
Ibogaine found in Root
Anticonvulsant
Ibogaine found in Root
Antidepressant
Ibogaine found in Root
Antidiarrheic
Tannin found in Root
Antidysenteric
Tannin found in Root
Antifatigue
Ibogaine found in Root
Antihepatotoxic
Tannin found in Root
Antihypertensive
Tannin found in Root
Antilipolytic
Tannin found in Root
Antimalarial
Voacangine found in Root
Antimutagenic
Tannin found in Root
Antinephritic
Tannin found in Root
Antiophidic
Tannin found in Root
Antioxidant
Tannin found in Root
Antiplasmodial
Voacangine found in Root
Antiradicular
Tannin found in Root
Antirenitic
Tannin found in Root
Antitumor-Promoter
Tannin found in Root
Antitumor
Tannin found in Root
Antiulcer
Tannin found in Root
Antiviral
Tannin found in Root
Apertif
Ibogaine found in Root
Bradycardic
Ibogaine found in Root
Ibogaline found in Stem Bark
Ibogamine found in Root
Iboxygaine found in Root
CNS-Stimulant
Ibogaine found in Root
Ibogaline found in Stem Bark
Iboxygaine found in Root
Tabernanthine found in Root
Voacangine found in Root
Voacristine found in Root
Cancer-Preventive
Tannin found in Root
Carcinogenic
Tannin found in Root
Cardiotonic
Voacangine found in Root
Chelator
Tannin found in Root
Cyclooxygenase-Inhibitor
Tannin found in Root
Cytotoxic
Ibogamine found in Root
Diuretic
Ibogaine found in Root
Glucosyl-Transferase-Inhibitor
Tannin found in Root
Hallucinogenic
Ibogaine found in Root
Hepatoprotective
Tannin found in Root
Hypotensive
Ibogaine found in Root
Ibogaline found in Stem Bark
Ibogamine found in Root
Iboxygaine found in Root
Voacangine found in Root
Hypothermic
Ibogaine found in Root
Immunosuppressant
Tannin found in Root
Lipoxygenase-Inhibitor
Tannin found in Root
MAO-Inhibitor
Tannin found in Root
Neurotoxic
Ibogaine found in Root
Ornithine-Decarboxylase-Inhibitor
Tannin found in Root
Pesticide
Tannin found in Root
Psychotomimetic
Ibogaine found in Root
Psychotropic
Tannin found in Root
Serotoninergic
Ibogaine found in Root
Xanthine-Oxidase-Inhibitor
Tannin found in Root

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Chemicals detected

Chemical Plant part Low ppm High ppm
Alkaloids Leaf 8,000
Root 55,000 60,000
Stem Bark 20,000
Seed 6,000 8,000
Desmethoxyiboluteine Root
Epiibogamine Plant
Gabonine Root
Hydroxyindoleinibogaine Root
Hydroxyindoleinibogamine Root
Ibagamine Root
Ibochine Root
Ibogaine Root
Ibogaline Stem Bark
Ibogamine Root
Iboluteine Root
Ibophyllidine Leaf
Iboxygaine Root
Iboxyphylline Leaf
Kimvuline Root
Kisantine Root
Pandoline Leaf
Tabernanthine Root
Tannin Root
Tubotaiwine Tissue Culture
Voacangine Root
Voacristine Root
Voaphylline Leaf
Reference: Dr. Duke's Phytochemical and Ethnobotanical Databases. [Online Database]