Strychnos nux-vomica Health effects and herbal facts

The strychnine tree also known as nux vomica, poison nut, semen strychnos and quaker buttons, is a deciduous tree native to India, and southeast Asia. It is a medium-sized tree in the family Loganiaceae that grows in open habitats. Its leaves are ovate and 2–3.5 inches in size. It is a major source of the highly poisonous, intensely bitter alkaloids strychnine and brucine, derived from the seeds inside the tree's round, green to orange fruit. The seeds contain approximately 1.5% strychnine, and the dried blossoms contain 1.0%. However, the tree's bark also contains brucine and other poisonous compounds. The use of strychnine is highly regulated in many countries, and is mostly used in baits to kill feral mammals, including wild dogs, foxes, and rodents. Most accidental poisoning is by breathing in the powder or by absorption through the skin.

Strychnos nux-vomica

Medical use

Gallery

Strychnos nux-vomica Strychnos nux-vomica Strychnos nux-vomica Strychnos nux-vomica Strychnos nux-vomica Strychnos nux-vomica Strychnos nux-vomica Strychnos nux-vomica Strychnos nux-vomica Strychnos nux-vomica Strychnos nux-vomica Strychnos nux-vomica Strychnos nux-vomica Strychnos nux-vomica

Biological activities

5-Alpha-Reductase-Inhibitor
Linoleic-acid found in Seed (4600 ppm)
Oleic-acid found in Seed (31000 ppm)
Palmitic-acid found in Seed (6300 ppm)
Stearic-acid found in Seed (3300 ppm)
Aldose-Reductase-Inhibitor
Chlorogenic-acid found in Seed
Allelochemic
Chlorogenic-acid found in Seed
Allergenic
Chlorogenic-acid found in Seed
Oleic-acid found in Seed (31000 ppm)
Alpha-Reductase-Inhibitor
Oleic-acid found in Seed (31000 ppm)
Analeptic
Strychnine found in Bark (15800 ppm);found in Seed (12000 ppm);found in Leaf (8000 ppm);found in Root (7030 ppm)
Analgesic
Alpha-amyrin found in Seed
Chlorogenic-acid found in Seed
Anemiagenic
Oleic-acid found in Seed (31000 ppm)
Anesthetic
Nor-macusine found in Seed
AntiEBV
Chlorogenic-acid found in Seed
AntiHIV
Chlorogenic-acid found in Seed
AntiLegionella
Chlorogenic-acid found in Seed
AntiMS
Linoleic-acid found in Seed (4600 ppm)
AntiUTI
Mannose found in Seed
Antiacne
Linoleic-acid found in Seed (4600 ppm)
Antiadhesive
Mannose found in Seed
Antialopecic
Linoleic-acid found in Seed (4600 ppm)
Oleic-acid found in Seed (31000 ppm)
Palmitic-acid found in Seed (6300 ppm)
Antialzheimeran
Choline found in Seed
Antianaphylactic
Linoleic-acid found in Seed (4600 ppm)
Antiandrogenic
Linoleic-acid found in Seed (4600 ppm)
Oleic-acid found in Seed (31000 ppm)
Palmitic-acid found in Seed (6300 ppm)
Antiapneic
Strychnine found in Bark (15800 ppm);found in Seed (12000 ppm);found in Leaf (8000 ppm);found in Root (7030 ppm)
Antiarteriosclerotic
Linoleic-acid found in Seed (4600 ppm)
Antiarthritic
Linoleic-acid found in Seed (4600 ppm)
Antiatherosclerotic
Chlorogenic-acid found in Seed
Antibacterial
Chlorogenic-acid found in Seed
Cycloartenol found in Seed
Anticarcinogenic
Chlorogenic-acid found in Seed
Antichoreic
Choline found in Seed
Anticirrhotic
Choline found in Seed
Anticoronary
Linoleic-acid found in Seed (4600 ppm)
Anticystinuric
Choline found in Seed
Anticystitic
Mannose found in Seed
Antidementia
Choline found in Seed
Antidiabetic
Chlorogenic-acid found in Seed
Choline found in Seed
Xylose found in Seed
Antidote
Strychnine found in Bark (15800 ppm);found in Seed (12000 ppm);found in Leaf (8000 ppm);found in Root (7030 ppm)
Antidyskinetic
Choline found in Seed
Antieczemic
Linoleic-acid found in Seed (4600 ppm)
Antiedemic
Alpha-amyrin found in Seed
Loganin found in Fruit
Antifeedant
Chlorogenic-acid found in Seed
Antifibrinolytic
Linoleic-acid found in Seed (4600 ppm)
Palmitic-acid found in Seed (6300 ppm)
Antigenotoxic
Chlorogenic-acid found in Seed
Antigonadotropic
Chlorogenic-acid found in Seed
Antigranular
Linoleic-acid found in Seed (4600 ppm)
Antihemolytic
Chlorogenic-acid found in Seed
Antihepatotoxic
Chlorogenic-acid found in Seed
Stigmasterol found in Seed
Antiherpetic
Chlorogenic-acid found in Seed
Antihistaminic
Chlorogenic-acid found in Seed
Linoleic-acid found in Seed (4600 ppm)
Antihomocysteine
Choline found in Seed
Antihypercholesterolemic
Chlorogenic-acid found in Seed
Antihyperglycemic
Strychnine found in Bark (15800 ppm);found in Seed (12000 ppm);found in Leaf (8000 ppm);found in Root (7030 ppm)
Antihyperthyroid
Chlorogenic-acid found in Seed
Antiinflammatory
Alpha-amyrin found in Seed
Chlorogenic-acid found in Seed
Cycloartenol found in Seed
Linoleic-acid found in Seed (4600 ppm)
Loganin found in Fruit
Oleic-acid found in Seed (31000 ppm)
Stigmasterol found in Seed
Antileukotriene-D4
Linoleic-acid found in Seed (4600 ppm)
Oleic-acid found in Seed (31000 ppm)
Antileukotriene
Chlorogenic-acid found in Seed
Antimalarial
Icajine found in Fruit (60 ppm)
Isostrychnine found in Seed
Vomicine found in Fruit (910 ppm)
Antimanic
Choline found in Seed
Antimelanogenic
Chlorogenic-acid found in Seed
Antimenorrhagic
Linoleic-acid found in Seed (4600 ppm)
Antimutagenic
Chlorogenic-acid found in Seed
Antinitrosaminic
Chlorogenic-acid found in Seed
Antinociceptive
Alpha-amyrin found in Seed
Choline found in Seed
Stigmasterol found in Seed
Antiophidic
Stigmasterol found in Seed
Antioxidant
Brucine found in Bark (48000 ppm);found in Leaf (8000 ppm);found in Root (2770 ppm);found in Seed (16000 ppm);found in Fruit (650 ppm)
Chlorogenic-acid found in Seed
Myristic-acid found in Seed (450 ppm)
Palmitic-acid found in Seed (6300 ppm)
Stigmasterol found in Seed
Strychnine found in Bark (15800 ppm);found in Seed (12000 ppm);found in Leaf (8000 ppm);found in Root (7030 ppm)
Antiperoxidant
Chlorogenic-acid found in Seed
Antiplasmodial
Icajine found in Fruit (60 ppm)
Isostrychnine found in Seed
Vomicine found in Fruit (910 ppm)
Antipolio
Chlorogenic-acid found in Seed
Antiprostatitic
Linoleic-acid found in Seed (4600 ppm)
Antiradicular
Chlorogenic-acid found in Seed
Antirheumatic
Cycloartenol found in Seed
Antiseptic
Chlorogenic-acid found in Seed
Antistaphylococcic
Cycloartenol found in Seed
Antisteatotic
Choline found in Seed
Antisunburn
Chlorogenic-acid found in Seed
Antithyroid
Chlorogenic-acid found in Seed
Antitumor-Promoter
Chlorogenic-acid found in Seed
Antitumor
Alpha-amyrin found in Seed
Chlorogenic-acid found in Seed
Antiulcer
Alpha-amyrin found in Seed
Chlorogenic-acid found in Seed
Antiviral
Chlorogenic-acid found in Seed
Stigmasterol found in Seed
Apertif
Strychnine found in Bark (15800 ppm);found in Seed (12000 ppm);found in Leaf (8000 ppm);found in Root (7030 ppm)
Artemicide
Stigmasterol found in Seed
Autotoxic
Chlorogenic-acid found in Seed
CNS-Active
Chlorogenic-acid found in Seed
CNS-Stimulant
Brucine found in Bark (48000 ppm);found in Leaf (8000 ppm);found in Root (2770 ppm);found in Seed (16000 ppm);found in Fruit (650 ppm)
Chlorogenic-acid found in Seed
Strychnine found in Bark (15800 ppm);found in Seed (12000 ppm);found in Leaf (8000 ppm);found in Root (7030 ppm)
Cancer-Preventive
Chlorogenic-acid found in Seed
Linoleic-acid found in Seed (4600 ppm)
Myristic-acid found in Seed (450 ppm)
Oleic-acid found in Seed (31000 ppm)
Stigmasterol found in Seed
Canicide
Strychnine found in Bark (15800 ppm);found in Seed (12000 ppm);found in Leaf (8000 ppm);found in Root (7030 ppm)
Carcinogenic
Linoleic-acid found in Seed (4600 ppm)
Cardiodepressant
Choline found in Seed
Diaboline found in Seed
Cardioprotective
Chlorogenic-acid found in Seed
Cathartic
Loganin found in Fruit
Cerebrotonic
Choline found in Seed
Chemopreventive
Chlorogenic-acid found in Seed
Cholagogue
Chlorogenic-acid found in Seed
Choleretic
Chlorogenic-acid found in Seed
Oleic-acid found in Seed (31000 ppm)
Cholinergic
Choline found in Seed
Circulatory-Stimulant
Brucine found in Bark (48000 ppm);found in Leaf (8000 ppm);found in Root (2770 ppm);found in Seed (16000 ppm);found in Fruit (650 ppm)
Strychnine found in Bark (15800 ppm);found in Seed (12000 ppm);found in Leaf (8000 ppm);found in Root (7030 ppm)
Clastogenic
Chlorogenic-acid found in Seed
Collagen-Sparing
Chlorogenic-acid found in Seed
Comedolytic
Linoleic-acid found in Seed (4600 ppm)
Convulsant
Brucine found in Bark (48000 ppm);found in Leaf (8000 ppm);found in Root (2770 ppm);found in Seed (16000 ppm);found in Fruit (650 ppm)
Strychnine found in Bark (15800 ppm);found in Seed (12000 ppm);found in Leaf (8000 ppm);found in Root (7030 ppm)
Cosmetic
Behenic-acid found in Seed (850 ppm)
Myristic-acid found in Seed (450 ppm)
Stearic-acid found in Seed (3300 ppm)
Cytotoxic
Alpha-amyrin found in Seed
Dermatitigenic
Oleic-acid found in Seed (31000 ppm)
Diagnostic
Xylose found in Seed
Diuretic
Chlorogenic-acid found in Seed
Dye
Xylose found in Seed
Estrogenic
Stigmasterol found in Seed
FLavor
Oleic-acid found in Seed (31000 ppm)
Palmitic-acid found in Seed (6300 ppm)
Stearic-acid found in Seed (3300 ppm)
Fungicide
Chlorogenic-acid found in Seed
Gastroprotective
Alpha-amyrin found in Seed
Hemolytic
Palmitic-acid found in Seed (6300 ppm)
Hepatoprotective
Alpha-amyrin found in Seed
Chlorogenic-acid found in Seed
Choline found in Seed
Linoleic-acid found in Seed (4600 ppm)
Histamine-Inhibitor
Chlorogenic-acid found in Seed
Hypercholesterolemic
Myristic-acid found in Seed (450 ppm)
Palmitic-acid found in Seed (6300 ppm)
Hypocholesterolemic
Cycloartenol found in Seed
Linoleic-acid found in Seed (4600 ppm)
Oleic-acid found in Seed (31000 ppm)
Stearic-acid found in Seed (3300 ppm)
Stigmasterol found in Seed
Hypoglycemic
Chlorogenic-acid found in Seed
Hypotensive
Choline found in Seed
Diaboline found in Seed
Nor-macusine found in Seed
Ileorelaxant
Choline found in Seed
Immunomodulator
Linoleic-acid found in Seed (4600 ppm)
Immunostimulant
Chlorogenic-acid found in Seed
Insectifuge
Alpha-amyrin found in Seed
Chlorogenic-acid found in Seed
Linoleic-acid found in Seed (4600 ppm)
Oleic-acid found in Seed (31000 ppm)
Interferonogenic
Chlorogenic-acid found in Seed
Irritant
Oleic-acid found in Seed (31000 ppm)
Juvabional
Chlorogenic-acid found in Seed
Larvistat
Chlorogenic-acid found in Seed
Laxative
Loganin found in Fruit
Leukotriene-Inhibitor
Chlorogenic-acid found in Seed
Lipotropic
Choline found in Seed
Lipoxygenase-Inhibitor
Chlorogenic-acid found in Seed
Lubricant
Myristic-acid found in Seed (450 ppm)
Palmitic-acid found in Seed (6300 ppm)
Stearic-acid found in Seed (3300 ppm)
Memorigenic
Choline found in Seed
Metal-Chelator
Chlorogenic-acid found in Seed
Metastatic
Linoleic-acid found in Seed (4600 ppm)
Myorelaxant
Diaboline found in Seed
NO-Genic
Chlorogenic-acid found in Seed
Nematicide
Linoleic-acid found in Seed (4600 ppm)
Myristic-acid found in Seed (450 ppm)
Palmitic-acid found in Seed (6300 ppm)
Ornithine-Decarboxylase-Inhibitor
Chlorogenic-acid found in Seed
Oviposition-Stimulant
Chlorogenic-acid found in Seed
Ovulant
Stigmasterol found in Seed
Paralytic
Diaboline found in Seed
Parasympathomimetic
Choline found in Seed
Percutaneostimulant
Oleic-acid found in Seed (31000 ppm)
Perfumery
Oleic-acid found in Seed (31000 ppm)
Stearic-acid found in Seed (3300 ppm)
Peristaltic
Strychnine found in Bark (15800 ppm);found in Seed (12000 ppm);found in Leaf (8000 ppm);found in Root (7030 ppm)
Pesticide
Brucine found in Bark (48000 ppm);found in Leaf (8000 ppm);found in Root (2770 ppm);found in Seed (16000 ppm);found in Fruit (650 ppm)
Chlorogenic-acid found in Seed
Cycloartenol found in Seed
Palmitic-acid found in Seed (6300 ppm)
Propecic
Linoleic-acid found in Seed (4600 ppm)
Oleic-acid found in Seed (31000 ppm)
Palmitic-acid found in Seed (6300 ppm)
Stearic-acid found in Seed (3300 ppm)
Rodenticide
Strychnine found in Bark (15800 ppm);found in Seed (12000 ppm);found in Leaf (8000 ppm);found in Root (7030 ppm)
Sedative
Stigmasterol found in Seed
Soap
Palmitic-acid found in Seed (6300 ppm)
Stimulant
Strychnine found in Bark (15800 ppm);found in Seed (12000 ppm);found in Leaf (8000 ppm);found in Root (7030 ppm)
Sunscreen
Chlorogenic-acid found in Seed
Suppository
Stearic-acid found in Seed (3300 ppm)
Sweetener
Chlorogenic-acid found in Seed
Galactose found in Seed
Sympatholytic
Nor-macusine found in Seed
Termitifuge
Brucine found in Bark (48000 ppm);found in Leaf (8000 ppm);found in Root (2770 ppm);found in Seed (16000 ppm);found in Fruit (650 ppm)
Tonic
Strychnine found in Bark (15800 ppm);found in Seed (12000 ppm);found in Leaf (8000 ppm);found in Root (7030 ppm)
Tremorigenic
Diaboline found in Seed
Ubiquiot
Cycloartenol found in Seed
Vulnerary
Chlorogenic-acid found in Seed

Search

Chemicals detected

Chemical Plant part Low ppm High ppm
16-hydroxy-alpha-colubrine Seed
16-hydroxy-beta-colubrine Seed
3-methoxyicajine Plant
4-deoxyloganin Plant
Alkaloids Bark 99,000
Root 9,900
Seed 2,500 50,000
Alpha-amyrin Seed
Alpha-colubrine Seed
Arabinose Seed
Arachidic-acid Seed 2,800 3,500
Behenic-acid Seed 680 850
Beta-colubrine Fruit 40
Brucine Bark 48,000
Leaf 8,000
Root 2,770
Seed 16,000
Fruit 300 650
Brucine-n-oxide Fruit 90 160
C-mavacurine Root Bark 1,000
Chlorogenic-acid Seed
Choline Seed
Condylocarpine Seed
Cycloartenol Seed
Diaboline Seed
Fat Seed 40,000 50,000
Galactose Seed
Geissoschizine Seed
Hydroxystrychnine Fruit 7 20
Icajine Fruit 20 60
Isostrychnine Seed
Linoleic-acid Seed 360 4,600
Loganic-acid Seed
Loganin Fruit
Mannose Seed
Myristic-acid Seed 360 450
N-methyl-sec-pseudo-beta-colubrine Fruit 7
Nor-macusine Seed
Novacine Fruit 180 200
Oleic-acid Seed 2,480 31,000
Palmitic-acid Seed 5,040 6,300
Pseudo-alpha-colubrine Seed
Pseudobrucine Fruit 30 80
Pseudostrychnine Fruit 20 30
Secologanin Fruit
Stearic-acid Seed 2,640 3,300
Stigmasterol Seed
Struxine Seed
Strychnicine Leaf 250
Strychnine Bark 15,800
Seed 400 12,000
Leaf 8,000
Root 7,030
Strychnine-n-6-oxide Fruit 20 50
Vomicine Fruit 130 910
Xylose Seed
Reference: Dr. Duke's Phytochemical and Ethnobotanical Databases. [Online Database]