Pilocarpus microphyllus Health effects and herbal facts

Known as
Pernambuco jaborandi

Pilocarpus microphyllus, the Maranham Jaborandi, is a plant species in the genus Pilocarpus found native to several states in northern Brazil. Commercial production of the alkaloid muscarinic receptor agonist pilocarpine is derived entirely from the leaves of the shrub.

Pilocarpus microphyllus

Medical use

Economic importance of Pilocarpus microphyllus

Medicines source of pilocarpine

Gallery

Pilocarpus microphyllus Pilocarpus microphyllus

Geografical distribution

  • SOUTHERN AMERICA
    Native
    • Northern South America: Suriname
    • Brazil: Brazil - Maranhao, Para, Piaui

Biological activities

AChE-Inhibitor
Limonene found in Leaf (50 ppm)
Acaricide
Limonene found in Leaf (50 ppm)
Aldose-Reductase-Inhibitor
Caryophyllene found in Leaf (475 ppm)
Delta-cadinene found in Leaf (165 ppm)
Allelochemic
Alpha-pinene found in Leaf (25 ppm)
Limonene found in Leaf (50 ppm)
Allergenic
Alpha-pinene found in Leaf (25 ppm)
Caryophyllene found in Leaf (475 ppm)
Limonene found in Leaf (50 ppm)
Alzheimerigenic
Pilocarpine found in Leaf (10000 ppm)
Analgesic
Caryophyllene found in Leaf (475 ppm)
Antiacetylcholinesterase
Limonene found in Leaf (50 ppm)
Antiacne
Alpha-pinene found in Leaf (25 ppm)
Caryophyllene found in Leaf (475 ppm)
Delta-cadinene found in Leaf (165 ppm)
Antiadenomic
Limonene found in Leaf (50 ppm)
Antiaggregant
Pilocarpine found in Leaf (10000 ppm)
Antiasthmatic
Caryophyllene found in Leaf (475 ppm)
Limonene found in Leaf (50 ppm)
Antibacterial
Alpha-pinene found in Leaf (25 ppm)
Caryophyllene found in Leaf (475 ppm)
Delta-cadinene found in Leaf (165 ppm)
Limonene found in Leaf (50 ppm)
Sabinene found in Leaf (90 ppm)
Anticancer
Limonene found in Leaf (50 ppm)
Anticariogenic
Caryophyllene found in Leaf (475 ppm)
Delta-cadinene found in Leaf (165 ppm)
Antidermatitic
Caryophyllene found in Leaf (475 ppm)
Antiedemic
Caryophyllene found in Leaf (475 ppm)
Antiesophagitic
Limonene found in Leaf (50 ppm)
Antifeedant
2-tridecanone found in Leaf (690 ppm)
Alpha-pinene found in Leaf (25 ppm)
Caryophyllene found in Leaf (475 ppm)
Limonene found in Leaf (50 ppm)
Antiflu
Alpha-pinene found in Leaf (25 ppm)
Limonene found in Leaf (50 ppm)
Antiglaucomic
Pilocarpine found in Leaf (10000 ppm)
Antihelicobacter
Sabinene found in Leaf (90 ppm)
Antiinflammatory
Alpha-pinene found in Leaf (25 ppm)
Caryophyllene found in Leaf (475 ppm)
Limonene found in Leaf (50 ppm)
Antileishmanic
Caryophyllene found in Leaf (475 ppm)
Antilithic
Limonene found in Leaf (50 ppm)
Antilymphomic
Limonene found in Leaf (50 ppm)
Antimalarial
Humulene found in Leaf (100 ppm)
Antimutagenic
Limonene found in Leaf (50 ppm)
Antiobesity
Limonene found in Leaf (50 ppm)
Antionychyotic
Caryophyllene found in Leaf (475 ppm)
Antiplasmodial
Humulene found in Leaf (100 ppm)
Antipneumonic
Alpha-pinene found in Leaf (25 ppm)
Antiproliferant
Caryophyllene found in Leaf (475 ppm)
Antiseptic
Alpha-pinene found in Leaf (25 ppm)
Limonene found in Leaf (50 ppm)
Sabinene found in Leaf (90 ppm)
Antispasmodic
Alpha-pinene found in Leaf (25 ppm)
Caryophyllene found in Leaf (475 ppm)
Limonene found in Leaf (50 ppm)
Antistaphylococcic
Alpha-pinene found in Leaf (25 ppm)
Caryophyllene found in Leaf (475 ppm)
Antistreptococcic
Caryophyllene found in Leaf (475 ppm)
Delta-cadinene found in Leaf (165 ppm)
Antitumor
Caryophyllene found in Leaf (475 ppm)
Limonene found in Leaf (50 ppm)
Antiulcer
Caryophyllene found in Leaf (475 ppm)
Sabinene found in Leaf (90 ppm)
Antiviral
Alpha-pinene found in Leaf (25 ppm)
Limonene found in Leaf (50 ppm)
Apoptotic
Limonene found in Leaf (50 ppm)
Bronchoprotectant
Limonene found in Leaf (50 ppm)
Cancer-Preventive
Alpha-pinene found in Leaf (25 ppm)
Limonene found in Leaf (50 ppm)
Candidicide
Caryophyllene found in Leaf (475 ppm)
Candidistat
Limonene found in Leaf (50 ppm)
Chemopreventive
Limonene found in Leaf (50 ppm)
Choleretic
Pilocarpine found in Leaf (10000 ppm)
Cholesterolytic
Limonene found in Leaf (50 ppm)
Cholinergic
Pilocarpine found in Leaf (10000 ppm)
Coleoptophile
Alpha-pinene found in Leaf (25 ppm)
Cytochrome-P450-Inducer
Delta-cadinene found in Leaf (165 ppm)
Detoxicant
Limonene found in Leaf (50 ppm)
Pilocarpine found in Leaf (10000 ppm)
Diaphoretic
Pilocarpine found in Leaf (10000 ppm)
Edemagenic
Pilocarpine found in Leaf (10000 ppm)
Enterocontractant
Limonene found in Leaf (50 ppm)
Expectorant
Alpha-pinene found in Leaf (25 ppm)
Limonene found in Leaf (50 ppm)
FLavor
Alpha-pinene found in Leaf (25 ppm)
Caryophyllene found in Leaf (475 ppm)
Limonene found in Leaf (50 ppm)
Fungicide
Caryophyllene found in Leaf (475 ppm)
Fungiphilic
Limonene found in Leaf (50 ppm)
Fungistat
Limonene found in Leaf (50 ppm)
GST-Inducer
Limonene found in Leaf (50 ppm)
Gastroprotective
Caryophyllene found in Leaf (475 ppm)
Gastrostimulant
Pilocarpine found in Leaf (10000 ppm)
Herbicide
Alpha-pinene found in Leaf (25 ppm)
Limonene found in Leaf (50 ppm)
Histaminic
Limonene found in Leaf (50 ppm)
Immunomodulator
Limonene found in Leaf (50 ppm)
Immunostimulant
Pilocarpine found in Leaf (10000 ppm)
Insecticide
Alpha-pinene found in Leaf (25 ppm)
Limonene found in Leaf (50 ppm)
Insectifuge
2-tridecanone found in Leaf (690 ppm)
Alpha-pinene found in Leaf (25 ppm)
Caryophyllene found in Leaf (475 ppm)
Limonene found in Leaf (50 ppm)
Insectiphile
Alpha-pinene found in Leaf (25 ppm)
Interleukin-6-Inhibitor
Limonene found in Leaf (50 ppm)
Irritant
Alpha-pinene found in Leaf (25 ppm)
Caryophyllene found in Leaf (475 ppm)
Limonene found in Leaf (50 ppm)
Ixodicide
Pilocarpine found in Leaf (10000 ppm)
Keratitigenic
Pilocarpine found in Leaf (10000 ppm)
Larvicide
Caryophyllene found in Leaf (475 ppm)
Lipolytic
Limonene found in Leaf (50 ppm)
Miotic
Pilocarpine found in Leaf (10000 ppm)
Mosquitocide
Caryophyllene found in Leaf (475 ppm)
Muscarinic-Agonist
Pilocarpine found in Leaf (10000 ppm)
Myorelaxant
Limonene found in Leaf (50 ppm)
NO-Genic
Limonene found in Leaf (50 ppm)
Nematicide
Limonene found in Leaf (50 ppm)
Ornithine-Decarboxylase-Inhibitor
Limonene found in Leaf (50 ppm)
Ozone-Scavenger
Limonene found in Leaf (50 ppm)
P450-2B1-Inhibitor
Alpha-pinene found in Leaf (25 ppm)
P450-Inducer
Delta-cadinene found in Leaf (165 ppm)
Limonene found in Leaf (50 ppm)
Parasympathomimetic
Pilocarpine found in Leaf (10000 ppm)
Perfumery
Alpha-pinene found in Leaf (25 ppm)
Caryophyllene found in Leaf (475 ppm)
Sabinene found in Leaf (90 ppm)
Peristaltic
Limonene found in Leaf (50 ppm)
Pesticide
2-tridecanone found in Leaf (690 ppm)
Alpha-pinene found in Leaf (25 ppm)
Caryophyllene found in Leaf (475 ppm)
Delta-cadinene found in Leaf (165 ppm)
Limonene found in Leaf (50 ppm)
Pilocarpine found in Leaf (10000 ppm)
Photosensitizer
Limonene found in Leaf (50 ppm)
Sedative
Alpha-pinene found in Leaf (25 ppm)
Caryophyllene found in Leaf (475 ppm)
Limonene found in Leaf (50 ppm)
Sialogogue
Pilocarpine found in Leaf (10000 ppm)
Spasmogenic
Alpha-pinene found in Leaf (25 ppm)
Sudorific
Pilocarpine found in Leaf (10000 ppm)
Sympathomimetic
Pilocarpine found in Leaf (10000 ppm)
Tachycardic
Pilocarpine found in Leaf (10000 ppm)
Termitifuge
Caryophyllene found in Leaf (475 ppm)
Testosterone-Inducer
Delta-cadinene found in Leaf (165 ppm)
Tranquilizer
Alpha-pinene found in Leaf (25 ppm)
Transdermal
Alpha-pinene found in Leaf (25 ppm)
Limonene found in Leaf (50 ppm)

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Chemicals detected

Chemical Plant part Low ppm High ppm
2-tridecanone Leaf 550 690
3,7,7-trimethylbicyclo(3.1.1)-2-heptene Leaf 300
Alpha-copaene Leaf 75 285
Alpha-guaiaene Leaf 110
Alpha-pinene Leaf 25
Beta-ocimene Leaf 25
Caryophyllene Leaf 450 475
Delta-cadinene Leaf 115 165
Eo Leaf 2,500 3,000
Humulene Leaf 100
Isoepipilosine Leaf
Isopilocarpidine Plant
Isopilocarpine Leaf
Limonene Leaf 50
Pilocarpidine Plant
Pilocarpine Leaf 6,000 10,000
Pilosine Leaf
Sabinene Leaf 90
Reference: Dr. Duke's Phytochemical and Ethnobotanical Databases. [Online Database]