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Hamamelis virginiana Health effects and herbal facts

Hamamelis virginiana, known as common or American witch-hazel, is a species of witch-hazel native to eastern North America, from Nova Scotia west to Minnesota, and south to central Florida to eastern Texas. It is a small, deciduous tree growing up to 6 m tall, often with a dense cluster of stems from its base. The bark is light brown, smooth, scaly, inner bark reddish purple. The branchlets are pubescent at first, later smooth, light orange brown, marked with occasional white dots, finally dark or reddish brown. The foliage buds are acute, slightly falcate, downy, light brown. The leaves are oval, 3.7–16.7 cm long and 2.5–13 cm broad, oblique at the base, acute or rounded at the apex, with a wavy-toothed or shallowly lobed margin, and a short, stout petiole 6–15 mm long; the midrib is more or less hairy, stout, with six to seven pairs of primary veins. The young leaves open involute, covered with stellate rusty down; when full grown, they are dark green above, and paler beneath. In fall, they turn yellow with rusty spots. The leaf stipules are lanceolate, acute; they fall soon after the leaf expands.

Medical use

Gallery

Geografical distribution

• NORTHERN AMERICA
  Native
  • Eastern Canada: Canada - New Brunswick , Nova Scotia, Ontario, Quebec
  • Northeastern U.S.A.: United States - Connecticut, Indiana, Maine, Massachusetts, Michigan, New Hampshire, New Jersey, New York, Ohio, Pennsylvania, Rhode Island, Vermont, West Virginia
  • North-Central U.S.A.: United States - Illinois, Iowa, Minnesota, Missouri, Oklahoma, Wisconsin
  • Southeastern U.S.A.: United States - Alabama , Arkansas, Delaware, Florida, Georgia, Kentucky, Louisiana, Maryland, Mississippi, North Carolina, South Carolina, Tennessee, Virginia
  • South-Central U.S.A.: United States - Texas
  • Northern Mexico: Mexico - Nuevo Leon, Tamaulipas

Biological activities

11B-HSD-Inhibitor	Kaempferol found in Leaf Quercetin found in Leaf
5-Lipoxygenase-Inhibitor	Kaempferol found in Leaf Quercetin found in Leaf
ACE-Inhibitor	Afzelin found in Leaf Astragalin found in Leaf Gallic-acid found in Leaf (54400 ppm) Isoquercitrin found in Leaf Quercitrin found in Leaf
ATPase-Inhibitor	Quercetin found in Leaf
Addictive	Acetaldehyde found in Leaf (160 ppm)
Aldehyde-Oxidase-Inhibitor	Quercetin found in Leaf
Aldose-Reductase-Inhibitor	Astragalin found in Leaf Isoquercitrin found in Leaf Kaempferol found in Leaf Quercetin found in Leaf Quercitrin found in Leaf Spiraeoside found in Leaf
Allelochemic	Myricetin found in Leaf Quercetin found in Leaf
Allergenic	Alpha-ionone found in Leaf (175 ppm) Beta-ionone found in Leaf (50 ppm) Quercetin found in Leaf
Analgesic	Gallic-acid found in Leaf (54400 ppm) Phenol found in Bark Quercetin found in Leaf
Anesthetic	Phenol found in Bark Safrole found in Leaf (10 ppm)
AntiGTF	Quercetin found in Leaf
AntiHIV	Ellagitannin found in Bark Gallic-acid found in Leaf (54400 ppm) Myricetin found in Leaf Quercetin found in Leaf
AntiMRSA	Gallic-acid found in Leaf (54400 ppm)
AntiMS	Phenol found in Bark
AntiPMS	Quercetin found in Leaf
Antiadenovirus	Gallic-acid found in Leaf (54400 ppm)
Antiaflatoxin	Kaempferol found in Leaf Quercetin found in Leaf
Antiaggregant	Kaempferol found in Leaf Quercetin found in Leaf Safrole found in Leaf (10 ppm)
Antiaging	Quercetin found in Leaf
Antiallergenic	Gallic-acid found in Leaf (54400 ppm) Myricetin found in Leaf
Antiallergic	Ellagitannin found in Bark Kaempferol found in Leaf Quercetin found in Leaf
Antialzheimeran	Choline found in Leaf (2000 ppm) Quercetin found in Leaf
Antianaphylactic	Gallic-acid found in Leaf (54400 ppm) Quercetin found in Leaf
Antiangiogenic	Gallic-acid found in Leaf (54400 ppm) Quercetin found in Leaf
Antiarrhythmic	Quercitrin found in Leaf
Antiarthritic	Quercetin found in Leaf
Antiasthmatic	Gallic-acid found in Leaf (54400 ppm) Quercetin found in Leaf
Antiatherosclerotic	Quercetin found in Leaf
Antibacterial	Beta-ionone found in Leaf (50 ppm) Gallic-acid found in Leaf (54400 ppm) Isoquercitrin found in Leaf Kaempferol found in Leaf Myricetin found in Leaf Phenol found in Bark Quercetin found in Leaf Quercitrin found in Leaf Safrole found in Leaf (10 ppm)
Antibronchitic	Gallic-acid found in Leaf (54400 ppm)
Anticancer	Gallic-acid found in Leaf (54400 ppm) Isoquercitrin found in Leaf Kaempferol found in Leaf
Anticarcinomic	Gallic-acid found in Leaf (54400 ppm)
Anticariogenic	Beta-ionone found in Leaf (50 ppm) Quercetin found in Leaf
Anticataract	Quercetin found in Leaf Quercitrin found in Leaf
Antichoreic	Choline found in Leaf (2000 ppm)
Anticirrhotic	Choline found in Leaf (2000 ppm)
Anticolitic	Quercetin found in Leaf
Anticomplementary	Quercetin found in Leaf
Anticonvulsant	Safrole found in Leaf (10 ppm)
Anticystinuric	Choline found in Leaf (2000 ppm)
Anticystitic	Quercetin found in Leaf
Antidementia	Choline found in Leaf (2000 ppm)
Antidepressant	Quercetin found in Leaf
Antidermatitic	Quercetin found in Leaf
Antidiabetic	Choline found in Leaf (2000 ppm) Quercetin found in Leaf
Antidyskinetic	Choline found in Leaf (2000 ppm)
Antiedemic	Quercitrin found in Leaf
Antielastase	Isoquercitrin found in Leaf Quercetin found in Leaf
Antiencephalitic	Quercetin found in Leaf
Antiescherichic	Gallic-acid found in Leaf (54400 ppm) Quercetin found in Leaf
Antiestrogenic	Quercetin found in Leaf
Antifeedant	Isoquercitrin found in Leaf Myricetin found in Leaf Quercetin found in Leaf Quercitrin found in Leaf
Antifertility	Kaempferol found in Leaf
Antifibrinolytic	Gallic-acid found in Leaf (54400 ppm)
Antifibrosarcomic	Quercetin found in Leaf
Antiflu	Gallic-acid found in Leaf (54400 ppm) Quercetin found in Leaf Quercitrin found in Leaf
Antigastric	Myricetin found in Leaf Quercetin found in Leaf
Antigingivitic	Kaempferol found in Leaf Myricetin found in Leaf
Antigonadotrophic	Myricetin found in Leaf
Antigonadotropic	Quercetin found in Leaf
Antihemorrhagic	Quercitrin found in Leaf
Antihemorrhoidal	Phenol found in Bark
Antihepatomic	Saponins found in Leaf
Antihepatotoxic	Gallic-acid found in Leaf (54400 ppm) Quercetin found in Leaf Quercitrin found in Leaf
Antiherpetic	Gallic-acid found in Leaf (54400 ppm) Kaempferol found in Leaf Quercetin found in Leaf Quercitrin found in Leaf
Antihistaminic	Kaempferol found in Leaf Myricetin found in Leaf Quercetin found in Leaf
Antihomocysteine	Choline found in Leaf (2000 ppm)
Antihydrocoele	Phenol found in Bark
Antihydrophobic	Quercetin found in Leaf
Antihypertensive	Quercetin found in Leaf
Antiimplantation	Kaempferol found in Leaf
Antiincontinence	Phenol found in Bark
Antiinflammatory	Gallic-acid found in Leaf (54400 ppm) Isoquercitrin found in Leaf Kaempferol found in Leaf Leucodelphinidin found in Leaf Myricetin found in Leaf Quercetin found in Leaf Quercitrin found in Leaf
Antileishmanic	Gallic-acid found in Leaf (54400 ppm) Quercetin found in Leaf
Antileukemic	Astragalin found in Leaf Kaempferol found in Leaf Quercetin found in Leaf
Antileukotriene	Quercetin found in Leaf
Antilipoperoxidant	Quercetin found in Leaf
Antilymphocytic	Kaempferol found in Leaf
Antimalarial	Quercetin found in Leaf
Antimanic	Choline found in Leaf (2000 ppm)
Antimelanomic	Beta-ionone found in Leaf (50 ppm) Quercetin found in Leaf
Antimetastatic	Quercetin found in Leaf
Antimutagenic	Gallic-acid found in Leaf (54400 ppm) Kaempferol found in Leaf Myricetin found in Leaf Quercetin found in Leaf Quercitrin found in Leaf Saponins found in Leaf
Antimyocarditic	Quercetin found in Leaf
Antineoplastic	Leucodelphinidin found in Leaf
Antinitrosaminic	Gallic-acid found in Leaf (54400 ppm) Quercetin found in Leaf
Antinociceptive	Choline found in Leaf (2000 ppm) Isoquercitrin found in Leaf Quercetin found in Leaf
Antionychogryphotic	Phenol found in Bark
Antiotitic	Phenol found in Bark
Antioxidant	Ellagitannin found in Bark Gallic-acid found in Leaf (54400 ppm) Hamamelitannin found in Bark (30000 ppm);found in Leaf (80000 ppm) Isoquercitrin found in Leaf Kaempferol found in Leaf Myricetin found in Leaf Phenol found in Bark Quercetin found in Leaf Quercitrin found in Leaf Spiraeoside found in Leaf
Antipancreatitic	Quercetin found in Leaf
Antiperiodontal	Quercetin found in Leaf
Antiperiodontic	Kaempferol found in Leaf Myricetin found in Leaf
Antiperiodontitic	Gallic-acid found in Leaf (54400 ppm)
Antiperistaltic	Quercetin found in Leaf
Antipermeability	Quercetin found in Leaf
Antiperoxidant	Gallic-acid found in Leaf (54400 ppm) Quercetin found in Leaf
Antipharyngitic	Quercetin found in Leaf
Antiplaque	Kaempferol found in Leaf Myricetin found in Leaf Quercetin found in Leaf
Antiplasmodial	Quercetin found in Leaf
Antipodriac	Quercetin found in Leaf
Antipolio	Gallic-acid found in Leaf (54400 ppm) Quercetin found in Leaf
Antiproliferant	Quercetin found in Leaf
Antiprostanoid	Quercetin found in Leaf
Antiprostatitic	Phenol found in Bark Quercetin found in Leaf
Antiproteolytic	Gallic-acid found in Leaf (54400 ppm)
Antipsoriac	Quercetin found in Leaf
Antipurpuric	Quercitrin found in Leaf
Antipyruvetic	Phenol found in Bark
Antiradicular	Gallic-acid found in Leaf (54400 ppm) Isoquercitrin found in Leaf Kaempferol found in Leaf Quercetin found in Leaf
Antiseptic	Gallic-acid found in Leaf (54400 ppm) Kaempferol found in Leaf Myricetin found in Leaf Phenol found in Bark Safrole found in Leaf (10 ppm)
Antiserotonin	Kaempferol found in Leaf
Antisinusitic	Phenol found in Bark
Antispasmodic	Kaempferol found in Leaf Quercetin found in Leaf Quercitrin found in Leaf
Antispastic	Phenol found in Bark
Antistaphylococcic	Gallic-acid found in Leaf (54400 ppm) Kaempferol found in Leaf Quercitrin found in Leaf
Antisteatotic	Choline found in Leaf (2000 ppm)
Antistreptococcic	Quercetin found in Leaf
Antithiamin	Quercetin found in Leaf
Antithrombic	Quercetin found in Leaf
Antithrombogenic	Quercitrin found in Leaf
Antitrypanosomic	Quercetin found in Leaf
Antitumor-Promoter	Gallic-acid found in Leaf (54400 ppm) Isoquercitrin found in Leaf Kaempferol found in Leaf Quercetin found in Leaf
Antitumor	Beta-ionone found in Leaf (50 ppm) Ellagitannin found in Bark Gallic-acid found in Leaf (54400 ppm) Isoquercitrin found in Leaf Kaempferol found in Leaf Quercetin found in Leaf Quercitrin found in Leaf
Antiulcer	Kaempferol found in Leaf Quercetin found in Leaf Quercitrin found in Leaf
Antiviral	Gallic-acid found in Leaf (54400 ppm) Kaempferol found in Leaf Myricetin found in Leaf Phenol found in Bark Quercetin found in Leaf Quercitrin found in Leaf
Antiwrinkle	Phenol found in Bark
Apoptotic	Gallic-acid found in Leaf (54400 ppm) Kaempferol found in Leaf Myricetin found in Leaf Quercetin found in Leaf
Aromatase-Inhibitor	Kaempferol found in Leaf
Astringent	Gallic-acid found in Leaf (54400 ppm)
Bacteristat	Gallic-acid found in Leaf (54400 ppm) Quercetin found in Leaf
Bradycardiac	Quercetin found in Leaf
Bronchodilator	Gallic-acid found in Leaf (54400 ppm)
CNS-Depressant	Phenol found in Bark Quercitrin found in Leaf Safrole found in Leaf (10 ppm)
CNS-Stimulant	Safrole found in Leaf (10 ppm)
COMP-Inhibitor	Myricetin found in Leaf
COMT-Inhibitor	Quercetin found in Leaf
COX-2-Inhibitor	Kaempferol found in Leaf Quercetin found in Leaf
Calcium-Antagonist	Safrole found in Leaf (10 ppm)
Calmodulin-Antagonist	Quercetin found in Leaf
Cancer-Preventive	Beta-ionone found in Leaf (50 ppm) Gallic-acid found in Leaf (54400 ppm) Isoquercitrin found in Leaf Kaempferol found in Leaf Myricetin found in Leaf Phenol found in Bark Quercetin found in Leaf Quercitrin found in Leaf Safrole found in Leaf (10 ppm)
Candidicide	Gallic-acid found in Leaf (54400 ppm) Myricetin found in Leaf Quercetin found in Leaf
Capillarigenic	Isoquercitrin found in Leaf
Capillariprotective	Leucocyanidin found in Leaf Quercetin found in Leaf
Carcinogenic	Gallic-acid found in Leaf (54400 ppm) Kaempferol found in Leaf Phenol found in Bark Quercetin found in Leaf Safrole found in Leaf (10 ppm)
Cardiodepressant	Choline found in Leaf (2000 ppm)
Cardiotonic	Quercitrin found in Leaf
Cardiotoxic	Ellagitannin found in Bark Gallo-tannin found in Leaf
Carminative	Safrole found in Leaf (10 ppm)
Catabolic	Quercetin found in Leaf
Cerebrotonic	Choline found in Leaf (2000 ppm)
Choleretic	Gallic-acid found in Leaf (54400 ppm) Kaempferol found in Leaf Quercitrin found in Leaf Quinic-acid found in Leaf
Cholinergic	Choline found in Leaf (2000 ppm)
Controlled	Safrole found in Leaf (10 ppm)
Copper-Chelator	Kaempferol found in Leaf Quercetin found in Leaf
Cyclooxygenase-Activator	Quercitrin found in Leaf
Cyclooxygenase-Inhibitor	Gallic-acid found in Leaf (54400 ppm) Kaempferol found in Leaf Quercetin found in Leaf
Cytochrome-P450-1A2-Inhibitor	Quercetin found in Leaf
Cytochrome-P450-Inducer	Beta-ionone found in Leaf (50 ppm) Safrole found in Leaf (10 ppm)
Cytochrome-P488-Inducer	Safrole found in Leaf (10 ppm)
Cytotoxic	Gallic-acid found in Leaf (54400 ppm) Kaempferol found in Leaf Quercetin found in Leaf
DNA-Binder	Safrole found in Leaf (10 ppm)
Deiodinase-Inhibitor	Quercetin found in Leaf
Detoxicant	Quercitrin found in Leaf
Diaphoretic	Isoquercitrin found in Leaf
Differentiator	Quercetin found in Leaf
Diuretic	Isoquercitrin found in Leaf Kaempferol found in Leaf Myricetin found in Leaf Quercitrin found in Leaf
Dye	Quercitrin found in Leaf
Emetic	Phenol found in Bark
Estrogenic	Kaempferol found in Leaf Quercetin found in Leaf
Expectorant	Astragalin found in Leaf
Floral-Inhibitor	Gallic-acid found in Leaf (54400 ppm)
Fungicide	Acetaldehyde found in Leaf (160 ppm) Beta-ionone found in Leaf (50 ppm) Kaempferol found in Leaf Phenol found in Bark Quercetin found in Leaf
Glucosyl-Transferase-Inhibitor	Quercetin found in Leaf
HIV-RT-Inhibitor	Kaempferol found in Leaf Quercetin found in Leaf
Hemolytic	Phenol found in Bark
Hemostat	Gallic-acid found in Leaf (54400 ppm) Quercetin found in Leaf Quercitrin found in Leaf
Hepatocarcinogenic	Safrole found in Leaf (10 ppm)
Hepatomagenic	Quercetin found in Leaf
Hepatoprotective	Choline found in Leaf (2000 ppm) Gallic-acid found in Leaf (54400 ppm) Kaempferol found in Leaf Quercetin found in Leaf
Hepatoregenerative	Safrole found in Leaf (10 ppm)
Hepatotonic	Quercitrin found in Leaf
Hepatotoxic	Safrole found in Leaf (10 ppm)
Hypocholesterolemic	Beta-ionone found in Leaf (50 ppm)
Hypoglycemic	Myricetin found in Leaf Quercetin found in Leaf Quercitrin found in Leaf
Hypotensive	Astragalin found in Leaf Choline found in Leaf (2000 ppm) Isoquercitrin found in Leaf Kaempferol found in Leaf Quercitrin found in Leaf
Hypothermic	Safrole found in Leaf (10 ppm)
ICAM-1-Inhibitor	Kaempferol found in Leaf
Ileorelaxant	Choline found in Leaf (2000 ppm)
Immunomodulator	Gallic-acid found in Leaf (54400 ppm) Saponins found in Leaf
Immunostimulant	Astragalin found in Leaf Ellagitannin found in Bark Gallic-acid found in Leaf (54400 ppm)
Immunosuppressant	Gallic-acid found in Leaf (54400 ppm)
Inotropic	Kaempferol found in Leaf Quercetin found in Leaf
Insectiphile	Isoquercitrin found in Leaf Quercitrin found in Leaf
Insulin-Sparing	Gallic-acid found in Leaf (54400 ppm)
Insulinogenic	Quercetin found in Leaf
Interferonogenic	Ellagitannin found in Bark
Iodothyronine-Deiodinase-Inhibitor	Kaempferol found in Leaf
Irritant	Safrole found in Leaf (10 ppm)
JNK-Inhibitor	Kaempferol found in Leaf
Juvabional	Quercetin found in Leaf
Larvistat	Myricetin found in Leaf Quercetin found in Leaf
Lipotropic	Choline found in Leaf (2000 ppm)
Lipoxygenase-Inhibitor	Kaempferol found in Leaf Myricetin found in Leaf Quercetin found in Leaf
MAO-A-Inhibitor	Quercetin found in Leaf Quercitrin found in Leaf
MAO-Inhibitor	Kaempferol found in Leaf Quercitrin found in Leaf
MMP-9-Inhibitor	Quercetin found in Leaf
Mast-Cell-Stabilizer	Quercetin found in Leaf
Memorigenic	Choline found in Leaf (2000 ppm)
Metalloproteinase-Inhibitor	Quercetin found in Leaf
Mutagenic	Kaempferol found in Leaf Myricetin found in Leaf Quercetin found in Leaf Safrole found in Leaf (10 ppm)
Myorelaxant	Gallic-acid found in Leaf (54400 ppm)
NADH-Oxidase-Inhibitor	Quercetin found in Leaf
NEP-Inhibitor	Quercetin found in Leaf
NF-kB-Inhibitor	Quercetin found in Leaf
NO-Inhibitor	Gallic-acid found in Leaf (54400 ppm) Kaempferol found in Leaf Quercetin found in Leaf
NO-Synthase-Inhibitor	Quercetin found in Leaf
Natriuretic	Kaempferol found in Leaf
Nematicide	Beta-ionone found in Leaf (50 ppm) Safrole found in Leaf (10 ppm)
Nephrotoxic	Gallic-acid found in Leaf (54400 ppm)
Neuroprotective	Kaempferol found in Leaf Quercetin found in Leaf
Neurotoxic	Safrole found in Leaf (10 ppm)
Ornithine-Decarboxylase-Inhibitor	Quercetin found in Leaf
Oxidase-Inhibitor	Myricetin found in Leaf
P450-1A-Inducer	Alpha-ionone found in Leaf (175 ppm)
P450-2B-Inducer	Alpha-ionone found in Leaf (175 ppm)
P450-Inducer	Beta-ionone found in Leaf (50 ppm) Quercetin found in Leaf
P450-Inhibitor	Quercetin found in Leaf
PAF-Inhibitor	Kaempferol found in Leaf
PGE2-Inhibitor	Quercetin found in Leaf
PTK-Inhibitor	Quercetin found in Leaf
Paralytic	Quercitrin found in Leaf
Parasympathomimetic	Choline found in Leaf (2000 ppm)
Pediculicide	Safrole found in Leaf (10 ppm)
Perfume	Alpha-ionone found in Leaf (175 ppm)
Perfumery	Acetaldehyde found in Leaf (160 ppm) Safrole found in Leaf (10 ppm)
Pesticide	Acetaldehyde found in Leaf (160 ppm) Beta-ionone found in Leaf (50 ppm) Gallic-acid found in Leaf (54400 ppm) Isoquercitrin found in Leaf Kaempferol found in Leaf Myricetin found in Leaf Phenol found in Bark Quercetin found in Leaf Quercitrin found in Leaf Safrole found in Leaf (10 ppm)
Phospholipase-Inhibitor	Quercetin found in Leaf
Plasmodicide	Quercetin found in Leaf
Proliferant	Quercetin found in Leaf
Prostaglandin-Synthesis-Inhibitor	Quercetin found in Leaf
Protein-Kinase-C-Inhibitor	Quercetin found in Leaf
Protisticide	Kaempferol found in Leaf
Psychoactive	Safrole found in Leaf (10 ppm)
Quinone-Reductase-Inducer	Kaempferol found in Leaf Myricetin found in Leaf Quercetin found in Leaf Spiraeoside found in Leaf
Respiraparalytic	Acetaldehyde found in Leaf (160 ppm)
Reverse-Transcriptase-Inhibitor	Ellagitannin found in Bark Gallo-tannin found in Leaf
Rodenticide	Phenol found in Bark
Styptic	Gallic-acid found in Leaf (54400 ppm)
TNF-alpha-Inhibitor	Isoquercitrin found in Leaf Kaempferol found in Leaf Quercetin found in Leaf
Teratologic	Kaempferol found in Leaf Quercetin found in Leaf
Topoisomerase-I-Inhibitor	Gallic-acid found in Leaf (54400 ppm) Kaempferol found in Leaf Myricetin found in Leaf Quercetin found in Leaf
Topoisomerase-II-Inhibitor	Hamamelitannin found in Bark (30000 ppm);found in Leaf (80000 ppm) Isoquercitrin found in Leaf Kaempferol found in Leaf Myricetin found in Leaf Quercetin found in Leaf
Tremorigenic	Alpha-ionone found in Leaf (175 ppm) Safrole found in Leaf (10 ppm)
Trichomonicide	Beta-ionone found in Leaf (50 ppm)
Tumorigenic	Quercetin found in Leaf
Tyrosinase-Inhibitor	Acetaldehyde found in Leaf (160 ppm) Kaempferol found in Leaf Quercetin found in Leaf
Tyrosine-Kinase-Inhibitor	Myricetin found in Leaf Quercetin found in Leaf
Uterotrophic	Kaempferol found in Leaf
VEGF-Inhibitor	Quercetin found in Leaf
Vasodilator	Kaempferol found in Leaf Myricetin found in Leaf Phenol found in Bark Quercetin found in Leaf
Vasopressor	Quercitrin found in Leaf
Xanthine-Oxidase-Inhibitor	Gallic-acid found in Leaf (54400 ppm) Quercetin found in Leaf
cAMP-Phosphodiesterase-Inhibitor	Kaempferol found in Leaf Quercetin found in Leaf
iNOS-Inhibitor	Kaempferol found in Leaf Quercetin found in Leaf

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