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Petasites hybridus Health effects and herbal facts

Petasites hybridus, the butterbur is a herbaceous perennial plant in the family Asteraceae, native to Europe and northern Asia. The flowers are produced in the early spring, before the leaves appear; they are pale pink, with several inflorescences clustered on a 5–20 cm stem. The leaves are large, on stout 80–120 cm tall stems, round, with a diameter of 40–70 cm. It is also called bog rhubarb, Devil's hat and pestilence wort. Synonyms include P. officinalis, P. ovatus and P. vulgaris.

Medical use

Gallery

Geografical distribution

• ASIA-TEMPERATE
  Native
  • Western Asia: Turkey
  • Caucasus: Armenia; Georgia; Russian Federation - Ciscaucasia, Dagestan
• EUROPE
  Native
  • Northern Europe: Ireland; United Kingdom
  • Middle Europe: Austria; Belgium; Czech Republic; Germany; Hungary; Netherlands; Poland; Slovakia; Switzerland
  • East Europe: Belarus; Moldova; Russian Federation - European part; Ukraine
  • Southeastern Europe: Albania; Bosnia and Herzegovina; Bulgaria; Croatia; Greece; Italy ; Macedonia; Montenegro; Romania; Serbia; Slovenia
  • Southwestern Europe: France ; Spain
  Naturalized
  • Northern Europe: Denmark; Norway; Sweden
  • East Europe: Estonia; Latvia; Lithuania
• NORTHERN AMERICA
  Naturalized
  • Northeastern U.S.A.: United States - Michigan

Biological activities

11B-HSD-Inhibitor	Quercetin found in Leaf
5-Alpha-Reductase-Inhibitor	Linoleic-acid found in Root Oleic-acid found in Root Palmitic-acid found in Root Stearic-acid found in Root
5-Lipoxygenase-Inhibitor	Quercetin found in Leaf
ACE-Inhibitor	Astragalin found in Leaf Isoquercitrin found in Leaf
ATPase-Inhibitor	Quercetin found in Leaf
Abortifacient	Beta-bisabolene found in Rhizome
Alcohol-Dehydrogenase-Inhibitor	Inulin found in Rhizome (35000 ppm)
Aldehyde-Oxidase-Inhibitor	Quercetin found in Leaf
Aldose-Reductase-Inhibitor	Astragalin found in Leaf Isoquercitrin found in Leaf Quercetin found in Leaf
Allelochemic	Quercetin found in Leaf
Allergenic	Oleic-acid found in Root Protocatechuic-acid found in Rhizome Quercetin found in Leaf
Alpha-Glucosidase-Inhibitor	Protocatechuic-acid found in Rhizome
Alpha-Reductase-Inhibitor	Oleic-acid found in Root
Analgesic	Quercetin found in Leaf
Androgenic	Beta-sitosterol found in Root
Anemiagenic	Oleic-acid found in Root
Angiogenic	Beta-sitosterol found in Root
Anorexic	Beta-sitosterol found in Root
AntiGTF	Quercetin found in Leaf
AntiHIV	Quercetin found in Leaf
AntiLegionella	Protocatechuic-acid found in Rhizome
AntiMS	Linoleic-acid found in Root
AntiPMS	Quercetin found in Leaf
Antiacne	Linoleic-acid found in Root
Antiadenomic	Beta-sitosterol found in Root
Antiaflatoxin	Quercetin found in Leaf
Antiaggregant	Quercetin found in Leaf
Antiaging	Quercetin found in Leaf
Antiallergic	Quercetin found in Leaf
Antialopecic	Linoleic-acid found in Root Oleic-acid found in Root Palmitic-acid found in Root
Antialzheimeran	Choline found in Rhizome Quercetin found in Leaf
Antianaphylactic	Linoleic-acid found in Root Quercetin found in Leaf
Antiandrogenic	Beta-sitosterol found in Root Linoleic-acid found in Root Oleic-acid found in Root Palmitic-acid found in Root
Antiangiogenic	Quercetin found in Leaf
Antiarrhythmic	Protocatechuic-acid found in Rhizome
Antiarteriosclerotic	Linoleic-acid found in Root
Antiarthritic	Linoleic-acid found in Root Quercetin found in Leaf
Antiasthmatic	Protocatechuic-acid found in Rhizome Quercetin found in Leaf
Antiatheromic	Pectin found in Rhizome (18500 ppm)
Antiatherosclerotic	Quercetin found in Leaf
Antibacterial	Beta-sitosterol found in Root Isoquercitrin found in Leaf Lauric-acid found in Root Pectin found in Rhizome (18500 ppm) Protocatechuic-acid found in Rhizome Quercetin found in Leaf
Anticancer	Isoquercitrin found in Leaf
Anticariogenic	Quercetin found in Leaf
Anticataract	Quercetin found in Leaf
Antichoreic	Choline found in Rhizome
Anticirrhotic	Choline found in Rhizome
Anticlastogen	Protocatechuic-acid found in Rhizome
Anticolitic	Quercetin found in Leaf
Anticomplementary	Quercetin found in Leaf
Anticoronary	Linoleic-acid found in Root
Anticystinuric	Choline found in Rhizome
Anticystitic	Quercetin found in Leaf
Antidementia	Choline found in Rhizome
Antidepressant	Quercetin found in Leaf
Antidermatitic	Quercetin found in Leaf
Antidiabetic	Choline found in Rhizome Inulin found in Rhizome (35000 ppm) Pectin found in Rhizome (18500 ppm) Quercetin found in Leaf
Antidiarrheic	Inulin found in Rhizome (35000 ppm) Pectin found in Rhizome (18500 ppm)
Antidyskinetic	Choline found in Rhizome
Antieczemic	Linoleic-acid found in Root
Antiedemic	Beta-sitosterol found in Root
Antielastase	Isoquercitrin found in Leaf Quercetin found in Leaf
Antiencephalitic	Quercetin found in Leaf
Antienteritic	Pectin found in Rhizome (18500 ppm)
Antiescherichic	Quercetin found in Leaf
Antiestrogenic	Beta-sitosterol found in Root Quercetin found in Leaf
Antifeedant	Beta-sitosterol found in Root Isopetasin found in Leaf (1500 ppm);found in Rhizome ;found in Root Isoquercitrin found in Leaf Quercetin found in Leaf
Antifertility	Beta-sitosterol found in Root
Antifibrinolytic	Linoleic-acid found in Root Palmitic-acid found in Root
Antifibrosarcomic	Quercetin found in Leaf
Antiflu	Quercetin found in Leaf
Antigallstone	Pectin found in Rhizome (18500 ppm)
Antigastric	Quercetin found in Leaf
Antigastritic	Pectin found in Rhizome (18500 ppm)
Antigliomic	Beta-elemene found in Rhizome
Antigonadotrophic	Beta-sitosterol found in Root
Antigonadotropic	Quercetin found in Leaf
Antigranular	Linoleic-acid found in Root
Antihepatotoxic	Protocatechuic-acid found in Rhizome Quercetin found in Leaf Stigmasterol found in Root
Antiherpetic	Protocatechuic-acid found in Rhizome Quercetin found in Leaf
Antihistaminic	Linoleic-acid found in Root Quercetin found in Leaf
Antihomocysteine	Choline found in Rhizome
Antihydrophobic	Quercetin found in Leaf
Antihyperlipoproteinaemic	Beta-sitosterol found in Root
Antihypertensive	Quercetin found in Leaf
Antiinflammatory	Beta-santalene found in Root Beta-sitosterol found in Root Isoquercitrin found in Leaf Linoleic-acid found in Root N-hentriacontane found in Root Oleic-acid found in Root Protocatechuic-acid found in Rhizome Quercetin found in Leaf Stigmasterol found in Root
Antiischemic	Protocatechuic-acid found in Rhizome
Antileishmanic	Quercetin found in Leaf
Antileukemic	Astragalin found in Leaf Beta-sitosterol found in Root Protocatechuic-acid found in Rhizome Quercetin found in Leaf
Antileukotriene-D4	Linoleic-acid found in Root Oleic-acid found in Root
Antileukotriene	Quercetin found in Leaf
Antilipoperoxidant	Quercetin found in Leaf
Antilithic	Pectin found in Rhizome (18500 ppm)
Antilymphomic	Beta-sitosterol found in Root
Antimalarial	Quercetin found in Leaf
Antimanic	Choline found in Rhizome
Antimelanogenic	Protocatechuic-acid found in Rhizome
Antimelanomic	Quercetin found in Leaf
Antimenorrhagic	Linoleic-acid found in Root
Antimetastatic	Pectin found in Rhizome (18500 ppm) Quercetin found in Leaf
Antimutagenic	Beta-sitosterol found in Root N-nonacosane found in Root Pectin found in Rhizome (18500 ppm) Protocatechuic-acid found in Rhizome Quercetin found in Leaf
Antimyocarditic	Quercetin found in Leaf
Antinitrosaminic	Quercetin found in Leaf
Antinociceptive	Choline found in Rhizome Isoquercitrin found in Leaf Quercetin found in Leaf Stigmasterol found in Root
Antiobesity	Pectin found in Rhizome (18500 ppm)
Antiophidic	Beta-sitosterol found in Root Protocatechuic-acid found in Rhizome Stigmasterol found in Root
Antioxidant	Beta-sitosterol found in Root Campesterol found in Root Isoquercitrin found in Leaf Lauric-acid found in Root Myristic-acid found in Root Palmitic-acid found in Root Pentadecanoic-acid found in Root Protocatechuic-acid found in Rhizome Quercetin found in Leaf Stigmasterol found in Root
Antipancreatitic	Quercetin found in Leaf
Antiperiodontal	Quercetin found in Leaf
Antiperistaltic	Quercetin found in Leaf
Antipermeability	Quercetin found in Leaf
Antiperoxidant	Protocatechuic-acid found in Rhizome Quercetin found in Leaf
Antipharyngitic	Quercetin found in Leaf
Antiplaque	Quercetin found in Leaf
Antiplasmodial	Quercetin found in Leaf
Antipodriac	Quercetin found in Leaf
Antipolio	Quercetin found in Leaf
Antiprogestational	Beta-sitosterol found in Root
Antiproliferant	Beta-elemene found in Rhizome Quercetin found in Leaf
Antiprostaglandin	Beta-sitosterol found in Root
Antiprostanoid	Quercetin found in Leaf
Antiprostatadenomic	Beta-sitosterol found in Root
Antiprostatitic	Beta-sitosterol found in Root Linoleic-acid found in Root Quercetin found in Leaf
Antipsoriac	Quercetin found in Leaf
Antipyretic	Beta-sitosterol found in Root
Antiradicular	Isoquercitrin found in Leaf Protocatechuic-acid found in Rhizome Quercetin found in Leaf
Antirhinoviral	Beta-bisabolene found in Rhizome
Antiseptic	Protocatechuic-acid found in Rhizome
Antispasmodic	Isopetasin found in Leaf (1500 ppm);found in Rhizome ;found in Root Petasin found in Leaf (11490 ppm);found in Root ;found in Rhizome (15300 ppm);found in Plant Protocatechuic-acid found in Rhizome Quercetin found in Leaf
Antisteatotic	Choline found in Rhizome
Antistreptococcic	Quercetin found in Leaf
Antithiamin	Quercetin found in Leaf
Antithrombic	Quercetin found in Leaf
Antitrypanosomic	Quercetin found in Leaf
Antitumor-Promoter	Isoquercitrin found in Leaf Quercetin found in Leaf
Antitumor	Alpha-humulene found in Rhizome Isoquercitrin found in Leaf Quercetin found in Leaf Senecionine found in Leaf ;found in Plant ;found in Root
Antitussive	Pectin found in Rhizome (18500 ppm) Protocatechuic-acid found in Rhizome
Antiulcer	Beta-bisabolene found in Rhizome Pectin found in Rhizome (18500 ppm) Quercetin found in Leaf
Antiviral	Beta-bisabolene found in Rhizome Beta-sitosterol found in Root Lauric-acid found in Root Protocatechuic-acid found in Rhizome Quercetin found in Leaf Stigmasterol found in Root
Apoptotic	Beta-elemene found in Rhizome Beta-sitosterol found in Root Protocatechuic-acid found in Rhizome Quercetin found in Leaf
Artemicide	Beta-sitosterol found in Root Stigmasterol found in Root
Avifuge	Integerrimine found in Leaf ;found in Plant ;found in Root
Bacteristat	N-hexacosane found in Root Quercetin found in Leaf
Bifidogenic	Inulin found in Rhizome (35000 ppm)
Bradycardiac	Quercetin found in Leaf
COMT-Inhibitor	Quercetin found in Leaf
COX-1-Inhibitor	Lauric-acid found in Root
COX-2-Inhibitor	Lauric-acid found in Root Quercetin found in Leaf
Calcium-Antagonist	Isopetasin found in Leaf (1500 ppm);found in Rhizome ;found in Root
Calmodulin-Antagonist	Quercetin found in Leaf
Cancer-Preventive	Beta-sitosterol found in Root Isoquercitrin found in Leaf Linoleic-acid found in Root Myristic-acid found in Root Oleic-acid found in Root Pectin found in Rhizome (18500 ppm) Quercetin found in Leaf Stigmasterol found in Root
Candidicide	Beta-sitosterol found in Root Lauric-acid found in Root Quercetin found in Leaf
Capillarigenic	Isoquercitrin found in Leaf
Capillariprotective	Quercetin found in Leaf
Carcinogenic	Linoleic-acid found in Root Petasitenine found in Plant Protocatechuic-acid found in Rhizome Quercetin found in Leaf Senkirkine found in Plant ;found in Root
Cardiodepressant	Choline found in Rhizome
Cardioprotective	Protocatechuic-acid found in Rhizome
Caspase-8-Inducer	Beta-sitosterol found in Root
Catabolic	Quercetin found in Leaf
Cerebrotonic	Choline found in Rhizome
Chemopreventive	Pectin found in Rhizome (18500 ppm) Protocatechuic-acid found in Rhizome
Choleretic	Oleic-acid found in Root
Cholinergic	Choline found in Rhizome
Comedolytic	Linoleic-acid found in Root
Copper-Chelator	Quercetin found in Leaf
Cosmetic	Behenic-acid found in Root Myristic-acid found in Root N-hentriacontane found in Root Stearic-acid found in Root
Cyclooxygenase-Inhibitor	Quercetin found in Leaf
Cytochrome-P450-1A2-Inhibitor	Quercetin found in Leaf
Cytotoxic	Quercetin found in Leaf
Deiodinase-Inhibitor	Quercetin found in Leaf
Demulcent	Pectin found in Rhizome (18500 ppm)
Dermatitigenic	Oleic-acid found in Root
Diaphoretic	Isoquercitrin found in Leaf
Differentiator	Quercetin found in Leaf
Diuretic	Isoquercitrin found in Leaf N-hentriacontane found in Root
Estrogenic	Beta-sitosterol found in Root Quercetin found in Leaf Stigmasterol found in Root
Expectorant	Astragalin found in Leaf Inulin found in Rhizome (35000 ppm)
FLavor	Dodecanol found in Leaf Oleic-acid found in Root Palmitic-acid found in Root Stearic-acid found in Root
Febrifuge	Beta-sitosterol found in Root
Fungicide	Pectin found in Rhizome (18500 ppm) Protocatechuic-acid found in Rhizome Quercetin found in Leaf
Gastrostimulant	Inulin found in Rhizome (35000 ppm)
Glucosyl-Transferase-Inhibitor	Quercetin found in Leaf
Glutathione-Depleting	Protocatechuic-acid found in Rhizome
Gonadotrophic	Beta-sitosterol found in Root
HIV-RT-Inhibitor	Quercetin found in Leaf
Hemolytic	Palmitic-acid found in Root
Hemostat	Pectin found in Rhizome (18500 ppm) Quercetin found in Leaf
Hepatomagenic	Quercetin found in Leaf
Hepatoprotective	Beta-sitosterol found in Root Choline found in Rhizome Linoleic-acid found in Root Quercetin found in Leaf
Hepatotoxic	Integerrimine found in Leaf ;found in Plant ;found in Root Protocatechuic-acid found in Rhizome Senecionine found in Leaf ;found in Plant ;found in Root
Hypercholesterolemic	Lauric-acid found in Root Myristic-acid found in Root Palmitic-acid found in Root
Hypocholesterolemic	Beta-sitosterol found in Root Campesterol found in Root Inulin found in Rhizome (35000 ppm) Linoleic-acid found in Root Oleic-acid found in Root Pectin found in Rhizome (18500 ppm) Stearic-acid found in Root Stigmasterol found in Root
Hypoglycemic	Beta-sitosterol found in Root Inulin found in Rhizome (35000 ppm) Pectin found in Rhizome (18500 ppm) Quercetin found in Leaf
Hypolipidemic	Beta-sitosterol found in Root
Hypotensive	Astragalin found in Leaf Choline found in Rhizome Isoquercitrin found in Leaf Senecionine found in Leaf ;found in Plant ;found in Root
Ileorelaxant	Choline found in Rhizome
Immunomodulator	Linoleic-acid found in Root
Immunostimulant	Astragalin found in Leaf Inulin found in Rhizome (35000 ppm) Protocatechuic-acid found in Rhizome
Inotropic	Quercetin found in Leaf
Insectifuge	Linoleic-acid found in Root Oleic-acid found in Root
Insectiphile	Isoquercitrin found in Leaf
Insulinogenic	Quercetin found in Leaf
Irritant	Gamma-bisabolene found in Rhizome Oleic-acid found in Root
Juvabional	Quercetin found in Leaf
Larvistat	Quercetin found in Leaf
Laxative	Inulin found in Rhizome (35000 ppm)
Lipolytic	Inulin found in Rhizome (35000 ppm)
Lipotropic	Choline found in Rhizome
Lipoxygenase-Inhibitor	Quercetin found in Leaf
Lubricant	Myristic-acid found in Root Palmitic-acid found in Root Stearic-acid found in Root
MAO-A-Inhibitor	Quercetin found in Leaf
MMP-9-Inhibitor	Quercetin found in Leaf
Mast-Cell-Stabilizer	Quercetin found in Leaf
Memorigenic	Choline found in Rhizome
Metalloproteinase-Inhibitor	Quercetin found in Leaf
Metastatic	Linoleic-acid found in Root
Mutagenic	Integerrimine found in Leaf ;found in Plant ;found in Root Quercetin found in Leaf
NADH-Oxidase-Inhibitor	Quercetin found in Leaf
NEP-Inhibitor	Quercetin found in Leaf
NF-kB-Inhibitor	Quercetin found in Leaf
NO-Inhibitor	Quercetin found in Leaf
NO-Synthase-Inhibitor	Quercetin found in Leaf
Nematicide	Linoleic-acid found in Root Myristic-acid found in Root Palmitic-acid found in Root
Nephrotoxic	Protocatechuic-acid found in Rhizome
Neuroprotective	Quercetin found in Leaf
Ornithine-Decarboxylase-Inhibitor	Quercetin found in Leaf
Ovulant	Stigmasterol found in Root
P450-Inducer	Quercetin found in Leaf
P450-Inhibitor	Quercetin found in Leaf
PGE2-Inhibitor	Quercetin found in Leaf
PTK-Inhibitor	Quercetin found in Leaf
Parasympathomimetic	Choline found in Rhizome
Percutaneostimulant	Oleic-acid found in Root
Perfume	Gamma-bisabolene found in Rhizome
Perfumery	Alpha-humulene found in Rhizome Beta-bisabolene found in Rhizome Beta-santalene found in Root Oleic-acid found in Root Stearic-acid found in Root
Peristaltic	Pectin found in Rhizome (18500 ppm)
Pesticide	Beta-sitosterol found in Root Isopetasin found in Leaf (1500 ppm);found in Rhizome ;found in Root Isoquercitrin found in Leaf N-hexacosane found in Root Palmitic-acid found in Root Pectin found in Rhizome (18500 ppm) Protocatechuic-acid found in Rhizome Quercetin found in Leaf
Phagocytotic	Protocatechuic-acid found in Rhizome
Phospholipase-Inhibitor	Quercetin found in Leaf
Plasmodicide	Quercetin found in Leaf
Prebiotic	Inulin found in Rhizome (35000 ppm)
Probiotic	Inulin found in Rhizome (35000 ppm)
Probiotigenic	Inulin found in Rhizome (35000 ppm)
Proliferant	Quercetin found in Leaf
Propecic	Linoleic-acid found in Root Oleic-acid found in Root Palmitic-acid found in Root Stearic-acid found in Root
Prostaglandigenic	Protocatechuic-acid found in Rhizome
Prostaglandin-Synthesis-Inhibitor	Quercetin found in Leaf
Protein-Kinase-C-Inhibitor	Quercetin found in Leaf
Quinone-Reductase-Inducer	Quercetin found in Leaf
Secretogogue	Protocatechuic-acid found in Rhizome
Sedative	Angelic-acid found in Rhizome Stigmasterol found in Root
Soap	Palmitic-acid found in Root
Spermicide	Beta-sitosterol found in Root
Stomachic	Beta-bisabolene found in Rhizome
Suppository	Stearic-acid found in Root
TNF-alpha-Inhibitor	Isoquercitrin found in Leaf Quercetin found in Leaf
Teratologic	Quercetin found in Leaf
Topoisomerase-I-Inhibitor	Quercetin found in Leaf
Topoisomerase-II-Inhibitor	Isoquercitrin found in Leaf Quercetin found in Leaf
Tumorigenic	Quercetin found in Leaf
Tyrosinase-Inhibitor	Protocatechuic-acid found in Rhizome Quercetin found in Leaf
Tyrosine-Kinase-Inhibitor	Quercetin found in Leaf
Ubiquiot	Beta-sitosterol found in Root Protocatechuic-acid found in Rhizome
Ulcerogenic	Beta-sitosterol found in Root
VEGF-Inhibitor	Quercetin found in Leaf
Vasodilator	Isopetasin found in Leaf (1500 ppm);found in Rhizome ;found in Root Quercetin found in Leaf
Xanthine-Oxidase-Inhibitor	Quercetin found in Leaf
cAMP-Phosphodiesterase-Inhibitor	Quercetin found in Leaf
iNOS-Inhibitor	Quercetin found in Leaf

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