Hydnocarpus wightiana Health effects and herbal facts

Hydnocarpus wightiana or Chaulmoogra is a tree in the Achariaceae family. The oil from its seeds has been widely used in Indian medicine and Chinese traditional medicine for the treatment of leprosy. It entered early Western medicine in the nineteenth century before the era of sulfones and antibiotics for the treatment of several skin diseases and leprosy. The oil was prescribed for leprosy as a mixture suspended in gum or as an emulsion.

Hydnocarpus wightiana

Medical use

Gallery

Hydnocarpus wightiana Hydnocarpus wightiana Hydnocarpus wightiana Hydnocarpus wightiana

Biological activities

11B-HSD-Inhibitor
Apigenin found in Seed
5-Alpha-Reductase-Inhibitor
Oleic-acid found in Seed (41110 ppm)
Palmitic-acid found in Seed (11385 ppm)
Absorbent
Starch found in Fruit
Aldose-Reductase-Inhibitor
Chrysoeriol found in Seed
Luteolin found in Seed
Allergenic
Oleic-acid found in Seed (41110 ppm)
Alpha-Reductase-Inhibitor
Oleic-acid found in Seed (41110 ppm)
Anemiagenic
Oleic-acid found in Seed (41110 ppm)
Anthelmintic
Betulinic-acid found in Leaf (48.8 ppm);found in Stem Bark (66.6 ppm);found in Seed
AntiADD
Apigenin found in Seed
AntiHIV
Apigenin found in Seed
Betulinic-acid found in Leaf (48.8 ppm);found in Stem Bark (66.6 ppm);found in Seed
Luteolin found in Seed
Antiaflatoxin
Apigenin found in Seed
Antiaggregant
Apigenin found in Seed
Antiaging
Apigenin found in Seed
Antiallergic
Apigenin found in Seed
Luteolin found in Seed
Antialopecic
Oleic-acid found in Seed (41110 ppm)
Palmitic-acid found in Seed (11385 ppm)
Antiandrogenic
Oleic-acid found in Seed (41110 ppm)
Palmitic-acid found in Seed (11385 ppm)
Antiangiogenic
Apigenin found in Seed
Luteolin found in Seed
Antiarrhythmic
Apigenin found in Seed
Antiatherogenic
Luteolin found in Seed
Antibacterial
Apigenin found in Seed
Betulinic-acid found in Leaf (48.8 ppm);found in Stem Bark (66.6 ppm);found in Seed
Chaulmoogric-acid found in Seed (170775 ppm)
Hydnocarpic-acid found in Seed (308000 ppm)
Luteolin found in Seed
Anticancer
Betulinic-acid found in Leaf (48.8 ppm);found in Stem Bark (66.6 ppm);found in Seed
Anticarcinogenic
Luteolin found in Seed
Anticarcinomic
Betulinic-acid found in Leaf (48.8 ppm);found in Stem Bark (66.6 ppm);found in Seed
Luteolin found in Seed
Anticataract
Luteolin found in Seed
Anticomplementary
Apigenin found in Seed
Chrysoeriol found in Seed
Luteolin found in Seed
Antidermatic
Luteolin found in Seed
Antidermatitic
Apigenin found in Seed
Antiedemic
Betulinic-acid found in Leaf (48.8 ppm);found in Stem Bark (66.6 ppm);found in Seed
Antiestrogenic
Apigenin found in Seed
Luteolin found in Seed
Antifeedant
Luteolin found in Seed
Antifibrinolytic
Palmitic-acid found in Seed (11385 ppm)
Antiherpetic
Apigenin found in Seed
Luteolin found in Seed
Antihistaminic
Apigenin found in Seed
Luteolin found in Seed
Antiinflammatory
Apigenin found in Seed
Betulinic-acid found in Leaf (48.8 ppm);found in Stem Bark (66.6 ppm);found in Seed
Luteolin found in Seed
Oleic-acid found in Seed (41110 ppm)
Antilepric
Chaulmoogric-acid found in Seed (170775 ppm)
Hydnocarpic-acid found in Seed (308000 ppm)
Antileukemic
Apigenin found in Seed
Betulinic-acid found in Leaf (48.8 ppm);found in Stem Bark (66.6 ppm);found in Seed
Luteolin found in Seed
Antileukotriene-D4
Oleic-acid found in Seed (41110 ppm)
Antilymphomic
Luteolin found in Seed
Antimalarial
Betulinic-acid found in Leaf (48.8 ppm);found in Stem Bark (66.6 ppm);found in Seed
Antimelanomic
Apigenin found in Seed
Betulinic-acid found in Leaf (48.8 ppm);found in Stem Bark (66.6 ppm);found in Seed
Luteolin found in Seed
Antimetastatic
Apigenin found in Seed
Antimutagenic
Apigenin found in Seed
Chrysoeriol found in Seed
Luteolin found in Seed
Antineoplastic
Leucopelargonidin found in Fruit
Antinesidioblastosic
Starch found in Fruit
Antinociceptive
Betulinic-acid found in Leaf (48.8 ppm);found in Stem Bark (66.6 ppm);found in Seed
Luteolin found in Seed
Antioxidant
Apigenin found in Seed
Chrysoeriol found in Seed
Luteolin found in Seed
Palmitic-acid found in Seed (11385 ppm)
Antiperistaltic
Apigenin found in Seed
Antiplasmodial
Betulinic-acid found in Leaf (48.8 ppm);found in Stem Bark (66.6 ppm);found in Seed
Antipolio
Luteolin found in Seed
Antiproliferant
Apigenin found in Seed
Luteolin found in Seed
Antirhinoviral
Chrysoeriol found in Seed
Antisarcoidosic
Chaulmoogric-acid found in Seed (170775 ppm)
Antispasmodic
Apigenin found in Seed
Luteolin found in Seed
Antistress
Apigenin found in Seed
Antithyroid
Apigenin found in Seed
Antitumor
Apigenin found in Seed
Betulinic-acid found in Leaf (48.8 ppm);found in Stem Bark (66.6 ppm);found in Seed
Luteolin found in Seed
Antitussive
Luteolin found in Seed
Antiviral
Apigenin found in Seed
Betulinic-acid found in Leaf (48.8 ppm);found in Stem Bark (66.6 ppm);found in Seed
Chrysoeriol found in Seed
Luteolin found in Seed
Anxiolytic
Apigenin found in Seed
Aphidifuge
Luteolin found in Seed
Apoptotic
Apigenin found in Seed
Betulinic-acid found in Leaf (48.8 ppm);found in Stem Bark (66.6 ppm);found in Seed
Luteolin found in Seed
Aromatase-Inhibitor
Apigenin found in Seed
Luteolin found in Seed
Beta-Glucuronidase-Inhibitor
Apigenin found in Seed
Luteolin found in Seed
CNS-Depressant
Apigenin found in Seed
COX-1-Inhibitor
Apigenin found in Seed
COX-2-Inhibitor
Apigenin found in Seed
Calcium-Antagonist
Luteolin found in Seed
Cancer-Preventive
Apigenin found in Seed
Chrysoeriol found in Seed
Luteolin found in Seed
Oleic-acid found in Seed (41110 ppm)
Chemopreventive
Luteolin found in Seed
Choleretic
Apigenin found in Seed
Luteolin found in Seed
Oleic-acid found in Seed (41110 ppm)
Cyclooxygenase-Inhibitor
Apigenin found in Seed
Cytochrome-P450-1A1-Inhibitor
Apigenin found in Seed
Cytotoxic
Apigenin found in Seed
Betulinic-acid found in Leaf (48.8 ppm);found in Stem Bark (66.6 ppm);found in Seed
Luteolin found in Seed
DNA-Protective
Apigenin found in Seed
Deiodinase-Inhibitor
Apigenin found in Seed
Luteolin found in Seed
Dermatitigenic
Oleic-acid found in Seed (41110 ppm)
Differentiator
Apigenin found in Seed
Luteolin found in Seed
Diuretic
Apigenin found in Seed
Luteolin found in Seed
Emollient
Starch found in Fruit
Estrogenic
Apigenin found in Seed
Luteolin found in Seed
FLavor
Oleic-acid found in Seed (41110 ppm)
Palmitic-acid found in Seed (11385 ppm)
HIF-1alpha-Inhibitor
Apigenin found in Seed
Hemolytic
Palmitic-acid found in Seed (11385 ppm)
Hepatoprotective
Luteolin found in Seed
Hyaluronidase-Inhibitor
Apigenin found in Seed
Luteolin found in Seed
Hypercholesterolemic
Palmitic-acid found in Seed (11385 ppm)
Hypocholesterolemic
Luteolin found in Seed
Oleic-acid found in Seed (41110 ppm)
Hypotensive
Apigenin found in Seed
ICAM-1-Inhibitor
Apigenin found in Seed
Luteolin found in Seed
IKK-Inhibitor
Apigenin found in Seed
Luteolin found in Seed
Inotropic
Apigenin found in Seed
Insectifuge
Oleic-acid found in Seed (41110 ppm)
Interleukin-6-Inhibitor
Apigenin found in Seed
Iodothyronine-Deiodinase-Inhibitor
Luteolin found in Seed
Irritant
Oleic-acid found in Seed (41110 ppm)
Lipoxygenase-Inhibitor
Luteolin found in Seed
Lubricant
Palmitic-acid found in Seed (11385 ppm)
MAO-Inhibitor
Apigenin found in Seed
MAPK-Inhibitor
Apigenin found in Seed
Luteolin found in Seed
MMP-9-Inhibitor
Luteolin found in Seed
Metalloproteinase-Inhibitor
Luteolin found in Seed
Musculotropic
Apigenin found in Seed
Mutagenic
Apigenin found in Seed
Myorelaxant
Apigenin found in Seed
Luteolin found in Seed
NADH-Oxidase-Inhibitor
Apigenin found in Seed
NEP-Inhibitor
Luteolin found in Seed
NF-kB-Inhibitor
Apigenin found in Seed
Luteolin found in Seed
NO-Inhibitor
Luteolin found in Seed
NO-Synthase-Inhibitor
Apigenin found in Seed
Nematicide
Palmitic-acid found in Seed (11385 ppm)
Nodulation-Signal
Apigenin found in Seed
Ornithine-Decarboxylase-Inhibitor
Apigenin found in Seed
P21-Inducer
Apigenin found in Seed
PKC-Inhibitor
Apigenin found in Seed
PTK-Inhibitor
Apigenin found in Seed
Luteolin found in Seed
Percutaneostimulant
Oleic-acid found in Seed (41110 ppm)
Perfumery
Oleic-acid found in Seed (41110 ppm)
Pesticide
Apigenin found in Seed
Hydnocarpic-acid found in Seed (308000 ppm)
Luteolin found in Seed
Palmitic-acid found in Seed (11385 ppm)
Phospholipase-A2-Inhibitor
Betulinic-acid found in Leaf (48.8 ppm);found in Stem Bark (66.6 ppm);found in Seed
Polyamine-Synthesis-Inhibitor
Apigenin found in Seed
Poultice
Starch found in Fruit
Progestational
Apigenin found in Seed
Proliferant
Luteolin found in Seed
Propecic
Oleic-acid found in Seed (41110 ppm)
Palmitic-acid found in Seed (11385 ppm)
Prostaglandin-Synthesis-Inhibitor
Betulinic-acid found in Leaf (48.8 ppm);found in Stem Bark (66.6 ppm);found in Seed
Prostaglandin-Synthetase-Inhibitor
Luteolin found in Seed
Protein-Kinase-C-Inhibitor
Apigenin found in Seed
Luteolin found in Seed
Quinone-Reductase-Inducer
Apigenin found in Seed
Radioprotective
Apigenin found in Seed
Sedative
Apigenin found in Seed
Soap
Palmitic-acid found in Seed (11385 ppm)
Succinoxidase-Inhibitor
Luteolin found in Seed
Sunscreen
Apigenin found in Seed
TNF-alpha-Inhibitor
Apigenin found in Seed
Luteolin found in Seed
Topoisomerase-I-Inhibitor
Apigenin found in Seed
Luteolin found in Seed
Topoisomerase-II-Inhibitor
Apigenin found in Seed
Uterotrophic
Apigenin found in Seed
VEGF-Inhibitor
Apigenin found in Seed
Luteolin found in Seed
Vasodilator
Apigenin found in Seed
Luteolin found in Seed
Xanthine-Oxidase-Inhibitor
Apigenin found in Seed
Luteolin found in Seed
iNOS-Inhibitor
Apigenin found in Seed
Luteolin found in Seed

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Chemicals detected

Chemical Plant part Low ppm High ppm
Aleprestic-acid Seed
Alepric-acid Seed
Aleprolic-acid Seed
Aleprylic-acid Seed
Apigenin Seed
Arachnic-acid Seed
Ash Seed 38,300
Betulinic-acid Leaf 48.8
Stem Bark 66.6
Seed
Chaulmoogric-acid Seed 170,775
Chrysoeriol Seed
Dihydrochaulmoogric-acid Seed
Dihydrohydnocarpic-acid Seed
Fat Seed 632,500
Gorlic-acid Seed 77,165
Hydnocarpic-acid Seed 308,000
Hydnocarpin Fruit
Isogaleic-acid Seed
Leucopelargonidin Fruit
Lichenin Fruit
Luteolin Seed
Oleic-acid Seed 41,110
Palmitic-acid Seed 11,385
Starch Fruit
Taraktogenic-acid Seed
Water Seed 84,800
Reference: Dr. Duke's Phytochemical and Ethnobotanical Databases. [Online Database]