Croton lechleri Health effects and herbal facts

Known as
dragon's blood dragon's-blood croton

Croton lechleri is a species of flowering plant in the spurge family, Euphorbiaceae, that is native to northwestern South America. It is commonly known as Sangre de Grado or Sangre de Drago, both of which translate to "dragon's blood". They refer to the tree's thick red latex. The latex has medicinal properties, and is used by local peoples as a liquid bandage, applied to seal wounds, as it dries quickly to form a protective skin-like barrier. The latex also contains a number of chemicals, including taspine, that have wound-healing properties. Its use by native people has led to scientific study and observation of its in vitro antioxidant activity as well as its mutagenicity. Oligomeric proanthocyanidins, another kind of chemical contained in the latex, are being developed for the treatment of HIV-associated diarrhea under the name crofelemer. In January 2013, crofelemer, under the trade name Fulyzaq, was approved by the FDA for the treatment of HIV-associated diarrhea.

Croton lechleri

Economic importance of Croton lechleri

Medicines source of crofelemer & taspine

Gallery

Croton lechleri Croton lechleri Croton lechleri Croton lechleri

Geografical distribution

  • SOUTHERN AMERICA
    Native
    • Western South America: Bolivia; Colombia; Ecuador; Peru

Biological activities

5-Lipoxygenase-Inhibitor
(-)-epicatechin found in Plant
Abortifacient
Betaine found in Plant
Acaricide
Eugenol found in Plant
Gamma-terpinene found in Plant
Adrenalytic
Glaucine found in Leaf
Aldose-Reductase-Inhibitor
(-)-epigallocatechin found in Plant
Daucosterol found in Plant
Gamma-terpinene found in Plant
Myrcene found in Plant
Allelochemic
(-)-epicatechin found in Plant
Alpha-pinene found in Plant
Borneol found in Plant
Vanillin found in Plant
Allelopathic
Camphene found in Plant
Terpinen-4-ol found in Plant
Allergenic
Alpha-pinene found in Plant
Beta-pinene found in Plant
Dipentene found in Plant
Eugenol found in Plant
Lignans found in Plant
Myrcene found in Plant
Vanillin found in Plant
Analgesic
Borneol found in Plant
Eugenol found in Plant
Myrcene found in Plant
P-cymene found in Plant
Androgenic
Beta-sitosterol found in Plant
Anesthetic
Eugenol found in Plant
Angiogenic
Beta-sitosterol found in Plant
Anorexic
Beta-sitosterol found in Plant
Anthelmintic
Tannin found in Plant
AntiCVI
Proanthocyanidins found in Latex Exudate (900000 ppm)
AntiEBV
(-)-epicatechin found in Plant
AntiTNF
Eugenol found in Plant
Antiacetylcholine
Borneol found in Plant
Antiacetylcholinesterase
D-limonene found in Plant
Gamma-terpinene found in Plant
P-cymene found in Plant
Terpinen-4-ol found in Plant
Antiacne
(-)-epigallocatechin found in Plant
Alpha-pinene found in Plant
Terpinen-4-ol found in Plant
Antiadenomic
Beta-sitosterol found in Plant
Antiallergic
Procyanidin found in Latex Exudate
Terpinen-4-ol found in Plant
Antialopecic
Proanthocyanidins found in Latex Exudate (900000 ppm)
Antiamebic
(-)-epigallocatechin found in Plant
Antianaphylactic
(-)-epicatechin found in Plant
Antiandrogenic
Beta-sitosterol found in Plant
Antianemic
Vanillin found in Plant
Antiapoptotic
Taspine found in Latex Exudate (204000 ppm)
Antiarachidonate
Eugenol found in Plant
Antiasthmatic
Terpinen-4-ol found in Plant
Antiatherosclerotic
Proanthocyanidins found in Latex Exudate (900000 ppm)
Antibacillary
P-cymene found in Plant
Antibacterial
(-)-epicatechin found in Plant
(-)-epigallocatechin found in Plant
1,3,5-trimethoxybenzene found in Latex Exudate
2,4,6-trimethoxyphenol found in Latex Exudate
Alpha-pinene found in Plant
Beta-sitosterol found in Plant
Borneol found in Plant
Dipentene found in Plant
Eugenol found in Plant
Hardwickic-acid found in Plant
Korberin-a found in Plant
Korberin-b found in Plant
Lignin found in Plant
Magnoflorine found in Plant
Myrcene found in Plant
P-cymene found in Plant
Proanthocyanidins found in Latex Exudate (900000 ppm)
Procyanidin found in Latex Exudate
Tannin found in Plant
Terpinen-4-ol found in Plant
Antibiotic
Procyanidin found in Latex Exudate
Prodelphinidin found in Latex Exudate
Antibronchitic
Borneol found in Plant
Anticancer
Lignin found in Plant
Tannin found in Plant
Vanillin found in Plant
Anticarcinogenic
(-)-epigallocatechin found in Plant
Anticaries
(-)-epigallocatechin found in Plant
Anticariogenic
Tannin found in Plant
Anticonvulsant
Eugenol found in Plant
Myrcene found in Plant
Anticoronary
Lignin found in Plant
Antidermatitic
Procyanidin-b-4 found in Plant
Antidiabetic
(-)-epicatechin found in Plant
Proanthocyanidins found in Latex Exudate (900000 ppm)
Antidiarrheic
Lignin found in Plant
Tannin found in Plant
Antidrepanocytic
Vanillin found in Plant
Antidysenteric
Tannin found in Plant
Antiedemic
Beta-sitosterol found in Plant
Eugenol found in Plant
Proanthocyanidins found in Latex Exudate (900000 ppm)
Procyanidin found in Latex Exudate
Taspine found in Latex Exudate (204000 ppm)
Antiescherichic
Borneol found in Plant
Vanillin found in Plant
Antiestrogenic
Beta-sitosterol found in Plant
Eugenol found in Plant
Lignans found in Plant
Antiexudative
Procyanidin found in Latex Exudate
Antifeedant
Alpha-pinene found in Plant
Beta-sitosterol found in Plant
Borneol found in Plant
Eugenol found in Plant
Gamma-terpinene found in Plant
Isoboldine found in Plant
Antifertility
Beta-sitosterol found in Plant
Antiflu
Alpha-pinene found in Plant
P-cymene found in Plant
Antigastritic
Betaine found in Plant
Antigastrotic
Procyanidin-b-4 found in Plant
Antigenotoxic
Eugenol found in Plant
Antigiardial
(-)-epigallocatechin found in Plant
Antigliomic
Beta-elemene found in Plant
Antigonadotrophic
Beta-sitosterol found in Plant
Antihepatitic
(-)-epicatechin found in Plant
Antihepatotoxic
Tannin found in Plant
Antiherpetic
Eugenol found in Plant
Antihistaminic
Proanthocyanidins found in Latex Exudate (900000 ppm)
Antihomocystinuric
Betaine found in Plant
Antihyperglycemic
(-)-epicatechin found in Plant
Antihyperlipoproteinaemic
Beta-sitosterol found in Plant
Antihypertensive
Tannin found in Plant
Antiischemic
Proanthocyanidins found in Latex Exudate (900000 ppm)
Antikeratotic
Eugenol found in Plant
Antilactobacillic
Vanillin found in Plant
Antileukemic
(-)-epicatechin found in Plant
Beta-sitosterol found in Plant
Daucosterol found in Plant
Taspine found in Latex Exudate (204000 ppm)
Antileukotriene
(-)-epicatechin found in Plant
Antilipolytic
Tannin found in Plant
Antilipoperoxidant
(-)-epicatechin found in Plant
Antilisteria
Vanillin found in Plant
Antilymphomic
Beta-sitosterol found in Plant
Antimelanomic
D-limonene found in Plant
Antimitotic
Eugenol found in Plant
Antimycotic
Lignans found in Plant
Antimyoatrophic
Betaine found in Plant
Antinephritic
Tannin found in Plant
Antineuromuscular
Magnoflorine found in Plant
Antinitrosaminic
Lignin found in Plant
Myrcene found in Plant
Antinitrosating
Eugenol found in Plant
Antiobesity
Isoboldine found in Plant
Antiophidic
Beta-sitosterol found in Plant
Tannin found in Plant
Antiotitic
Borneol found in Plant
Antiperiodontal
Proanthocyanidins found in Latex Exudate (900000 ppm)
Antiplaque
Proanthocyanidins found in Latex Exudate (900000 ppm)
Antipneumonic
Alpha-pinene found in Plant
Antipolio
Vanillin found in Plant
Antiprogestational
Beta-sitosterol found in Plant
Antiproliferant
Beta-elemene found in Plant
Proanthocyanidins found in Latex Exudate (900000 ppm)
Antiprostatadenomic
Beta-sitosterol found in Plant
Antiprostatitic
Beta-sitosterol found in Plant
Antipyretic
Beta-sitosterol found in Plant
Borneol found in Plant
Eugenol found in Plant
Antirenitic
Tannin found in Plant
Antiretinopathic
Proanthocyanidins found in Latex Exudate (900000 ppm)
Antiretroviral
Antirheumatalgic
P-cymene found in Plant
Antisalmonella
Borneol found in Plant
Eugenol found in Plant
Antisarcomic
Taspine found in Latex Exudate (204000 ppm)
Antiseptic
Alpha-pinene found in Plant
Beta-pinene found in Plant
Eugenol found in Plant
Hardwickic-acid found in Plant
Proanthocyanidins found in Latex Exudate (900000 ppm)
Terpinen-4-ol found in Plant
Antisickling
Vanillin found in Plant
Antispasmodic
Alpha-pinene found in Plant
Beta-pinene found in Plant
Borneol found in Plant
Daucosterol found in Plant
Eugenol found in Plant
Glaucine found in Leaf
Magnoflorine found in Plant
Myrcene found in Plant
Terpinen-4-ol found in Plant
Antistaphylococcic
Alpha-pinene found in Plant
Borneol found in Plant
Eugenol found in Plant
Antistreptococcic
(-)-epigallocatechin found in Plant
Antistroke
Proanthocyanidins found in Latex Exudate (900000 ppm)
Antisuperoxidogenic
Glaucine found in Leaf
Antithromboxane
Eugenol found in Plant
Antitumor-Promoter
D-limonene found in Plant
Tannin found in Plant
Vanillin found in Plant
Antitumor
Daucosterol found in Plant
Eugenol found in Plant
Lignans found in Plant
Lignin found in Plant
Proanthocyanidins found in Latex Exudate (900000 ppm)
Tannin found in Plant
Vanillin found in Plant
Antitussive
Glaucine found in Leaf
Terpinen-4-ol found in Plant
Antiviral
(-)-epicatechin found in Plant
Alpha-pinene found in Plant
Beta-sitosterol found in Plant
Dipentene found in Plant
Eugenol found in Plant
Lignans found in Plant
Lignin found in Plant
P-cymene found in Plant
Proanthocyanidins found in Latex Exudate (900000 ppm)
Procyanidin found in Latex Exudate
Tannin found in Plant
Taspine found in Latex Exudate (204000 ppm)
Vanillin found in Plant
Antiyeast
Borneol found in Plant
Vanillin found in Plant
Apifuge
Eugenol found in Plant
Apoptotic
Beta-elemene found in Plant
Beta-sitosterol found in Plant
D-limonene found in Plant
Artemicide
Beta-sitosterol found in Plant
Bacteriostatic
Terpinen-4-ol found in Plant
Bacteristat
Vanillin found in Plant
Beta-Glucuronidase-Inhibitor
Proanthocyanidins found in Latex Exudate (900000 ppm)
Bruchiphobe
Betaine found in Plant
CNS-Depressant
Eugenol found in Plant
Magnoflorine found in Plant
CNS-Stimulant
Borneol found in Plant
CNS-Toxic
Borneol found in Plant
COMP-Inhibitor
(-)-epicatechin found in Plant
(-)-epigallocatechin found in Plant
Calcium-Antagonist
Eugenol found in Plant
Candidicide
Beta-pinene found in Plant
Beta-sitosterol found in Plant
Borneol found in Plant
Eugenol found in Plant
Vanillin found in Plant
Capillariprotective
Proanthocyanidins found in Latex Exudate (900000 ppm)
Procyanidin found in Latex Exudate
Carcinogenic
Tannin found in Plant
Cardioprotective
Betaine found in Plant
Proanthocyanidins found in Latex Exudate (900000 ppm)
Cardiovascular
Lignans found in Plant
Carminative
Eugenol found in Plant
Caspase-8-Inducer
Beta-sitosterol found in Plant
Cathartic
Lignans found in Plant
Chelator
Lignin found in Plant
Tannin found in Plant
Chemopreventive
D-limonene found in Plant
Myrcene found in Plant
Choleretic
Borneol found in Plant
Eugenol found in Plant
Vanillin found in Plant
Choline-Sparing
(-)-epicatechin found in Plant
Cicatrizant
Taspine found in Latex Exudate (204000 ppm)
Coleoptophile
Alpha-pinene found in Plant
Collagenase-Inhibitor
Proanthocyanidins found in Latex Exudate (900000 ppm)
Collagenic
Proanthocyanidins found in Latex Exudate (900000 ppm)
Curaroid
Magnoflorine found in Plant
Cytochrome-P450-Inhibitor
Eugenol found in Plant
Deodorant
Proanthocyanidins found in Latex Exudate (900000 ppm)
Differentiator
D-limonene found in Plant
Diuretic
Betaine found in Plant
Terpinen-4-ol found in Plant
Dopamine-Adenylate-Cyclase-Inhibitor
Isoboldine found in Plant
Elastase-Inhibitor
Proanthocyanidins found in Latex Exudate (900000 ppm)
Emmenagogue
Betaine found in Plant
Enterorelaxant
Eugenol found in Plant
Epitheliogenic
4-o-dimethylcedrusin found in Latex Exudate
Estrogenic
Beta-sitosterol found in Plant
Ethanolytic
Betaine found in Plant
Expectorant
Alpha-pinene found in Plant
Betaine found in Plant
Camphene found in Plant
Dipentene found in Plant
FLavor
Alpha-pinene found in Plant
Beta-pinene found in Plant
Borneol found in Plant
Camphene found in Plant
D-limonene found in Plant
Eugenol found in Plant
Gamma-terpinene found in Plant
Myrcene found in Plant
P-cymene found in Plant
Vanillin found in Plant
Febrifuge
Beta-sitosterol found in Plant
Fungicide
Borneol found in Plant
Eugenol found in Plant
Hardwickic-acid found in Plant
Isoboldine found in Plant
Myrcene found in Plant
P-cymene found in Plant
Terpinen-4-ol found in Plant
Vanillin found in Plant
Glucosyl-Transferase-Inhibitor
Tannin found in Plant
Gonadotrophic
Beta-sitosterol found in Plant
Herbicide
Alpha-pinene found in Plant
Beta-pinene found in Plant
Borneol found in Plant
Eugenol found in Plant
P-cymene found in Plant
Terpinen-4-ol found in Plant
Hyaluronidase-Inhibitor
Proanthocyanidins found in Latex Exudate (900000 ppm)
Procyanidin found in Latex Exudate
Hypocholesterolemic
(-)-epicatechin found in Plant
Beta-sitosterol found in Plant
D-limonene found in Plant
Lignin found in Plant
Hypoglycemic
(-)-epicatechin found in Plant
Beta-sitosterol found in Plant
Daucosterol found in Plant
Glaucine found in Leaf
Proanthocyanidins found in Latex Exudate (900000 ppm)
Hypolipidemic
Beta-sitosterol found in Plant
Hypotensive
Glaucine found in Leaf
Magnoflorine found in Plant
Hypothermic
Myrcene found in Plant
Immunosuppressant
Tannin found in Plant
Vanillin found in Plant
Inhalant
Borneol found in Plant
Insect-Repellent
Borneol found in Plant
Insecticide
Alpha-pinene found in Plant
D-limonene found in Plant
Eugenol found in Plant
Insectifuge
Alpha-pinene found in Plant
Beta-pinene found in Plant
Borneol found in Plant
Camphene found in Plant
D-limonene found in Plant
Eugenol found in Plant
Gamma-terpinene found in Plant
Myrcene found in Plant
P-cymene found in Plant
Terpinen-4-ol found in Plant
Insectiphile
Alpha-pinene found in Plant
Insulinogenic
(-)-epicatechin found in Plant
Irritant
Alpha-pinene found in Plant
Beta-pinene found in Plant
Borneol found in Plant
Dipentene found in Plant
Eugenol found in Plant
Gamma-terpinene found in Plant
Myrcene found in Plant
P-cymene found in Plant
Terpinen-4-ol found in Plant
Vanillin found in Plant
Juvabional
Eugenol found in Plant
Larvicide
Eugenol found in Plant
Laxative
Lignin found in Plant
P-cymene found in Plant
Lipotropic
Betaine found in Plant
Lipoxygenase-1-Inhibitor
(-)-epicatechin found in Plant
Lipoxygenase-Inhibitor
(-)-epicatechin found in Plant
(-)-epigallocatechin found in Plant
Epigallocatechin found in Latex Exudate
Tannin found in Plant
Litholytic
D-limonene found in Plant
MAO-Inhibitor
Tannin found in Plant
Motor-Depressant
Eugenol found in Plant
Mucogenic
Betaine found in Plant
Myorelaxant
Borneol found in Plant
Myrcene found in Plant
Nematicide
Borneol found in Plant
Eugenol found in Plant
Terpinen-4-ol found in Plant
Nephrotoxic
D-limonene found in Plant
Neurotoxic
Eugenol found in Plant
Ornithine-Decarboxylase-Inhibitor
Proanthocyanidins found in Latex Exudate (900000 ppm)
Tannin found in Plant
P450-2B1-Inhibitor
Alpha-pinene found in Plant
D-limonene found in Plant
Myrcene found in Plant
PAF-Inhibitor
Magnoflorine found in Plant
Pancreatogenic
(-)-epicatechin found in Plant
Paralytic
Magnoflorine found in Plant
Perfumery
Alpha-pinene found in Plant
Beta-pinene found in Plant
Borneol found in Plant
Eugenol found in Plant
Gamma-terpinene found in Plant
Myrcene found in Plant
Vanillin found in Plant
Peroxynitrite-Scavenger
(-)-epigallocatechin found in Plant
Pesticide
(-)-epicatechin found in Plant
(-)-epigallocatechin found in Plant
Alpha-pinene found in Plant
Beta-pinene found in Plant
Beta-sitosterol found in Plant
Betaine found in Plant
Borneol found in Plant
Camphene found in Plant
D-limonene found in Plant
Dipentene found in Plant
Eugenol found in Plant
Gamma-terpinene found in Plant
Hardwickic-acid found in Plant
Isoboldine found in Plant
Korberin-a found in Plant
Korberin-b found in Plant
Lignin found in Plant
Magnoflorine found in Plant
Myrcene found in Plant
P-cymene found in Plant
Procyanidin found in Latex Exudate
Tannin found in Plant
Terpinen-4-ol found in Plant
Vanillin found in Plant
Propecic
Proanthocyanidins found in Latex Exudate (900000 ppm)
Prostaglandin-Synthesis-Inhibitor
Eugenol found in Plant
Protisticide
(-)-epigallocatechin found in Plant
Psychotropic
Tannin found in Plant
Pyrogenic
Glaucine found in Leaf
Renoirritant
Terpinen-4-ol found in Plant
Respiradepressant
Glaucine found in Leaf
Reverse-Transcriptase-Inhibitor
(-)-epicatechin found in Plant
Taspine found in Latex Exudate (204000 ppm)
Sedative
Alpha-pinene found in Plant
Borneol found in Plant
Dipentene found in Plant
Eugenol found in Plant
P-cymene found in Plant
Spasmogenic
Alpha-pinene found in Plant
Beta-pinene found in Plant
Camphene found in Plant
Spermicide
Beta-sitosterol found in Plant
Terpinen-4-ol found in Plant
Termiticide
Eugenol found in Plant
Toxic
Magnoflorine found in Plant
Tranquilizer
Alpha-pinene found in Plant
Borneol found in Plant
Transdermal
Alpha-pinene found in Plant
Beta-pinene found in Plant
Trichomonicide
Eugenol found in Plant
P-cymene found in Plant
Trichomonistat
Eugenol found in Plant
Trypsin-Enhancer
Eugenol found in Plant
Tyrosine-Kinase-Inhibitor
Catechins found in Plant
Ubiquiot
Beta-sitosterol found in Plant
Ulcerogenic
Beta-sitosterol found in Plant
Eugenol found in Plant
Varroacide
Eugenol found in Plant
Vasodilator
(-)-epicatechin found in Plant
Eugenol found in Plant
Magnoflorine found in Plant
Proanthocyanidins found in Latex Exudate (900000 ppm)
Vasorelaxant
Proanthocyanidins found in Latex Exudate (900000 ppm)
Vermifuge
Eugenol found in Plant
Viristat
Taspine found in Latex Exudate (204000 ppm)
Vulnerary
Procyanidin-b-4 found in Plant
Taspine found in Latex Exudate (204000 ppm)
Terpinen-4-ol found in Plant

Search

Chemicals detected

Chemical Plant part Low ppm High ppm
(+)-catechin Plant
(+)-gallocatechin Plant
(-)-epicatechin Plant
(-)-epigallocatechin Plant
1,3,5-trimethoxybenzene Latex Exudate
2,4,6-trimethoxyphenol Latex Exudate
3',4-o-dimethylcedrusin Latex Exudate
3,4-dimethoxybenzenyl-alcohol Latex Exudate
3,4-dimethoxyphenol Plant
4-hydroxyphenethyl-alcohol Latex Exudate
4-hydroxyphenethyl-alcohol-acetate Latex Exudate
4-o-dimethylcedrusin Latex Exudate
Alkaloids Plant
Alpha-calacorene Plant
Alpha-copaene Plant
Alpha-pinene Plant
Alpha-thujene Plant
Beta-caryophyllene Plant
Beta-elemene Plant
Beta-pinene Plant
Beta-sitostenone Latex Exudate
Beta-sitosterol Plant
Beta-sitosterol-3-o-beta-d-glucopyranoside Plant
Betaine Plant
Bincatriol Plant
Borneol Plant
Calamenene Plant
Camphene Plant
Catechin-(4-alpha-8)-epicatechin Plant
Catechin-(4-alpha-8)-epigallocatechin Plant
Catechin-(4-alpha-8)-gallocatechin-(4-alpha-8)-epigallocatechin Plant
Catechins Plant
Crolechinic-acid Latex Exudate
Crolechinol Latex Exudate
Cuparophenol Plant
D-limonene Plant
Daucosterol Plant
Dihydrobenzofuran Plant
Dipentene Plant
Diterpenes Plant
Epigallocatechin Latex Exudate
Eugenol Plant
Euparophenol Plant
Flavan-3-ols Latex Exudate
Gallocatechin Latex Exudate
Gallocatechin-(4-alpha-8)-epicatechin Plant
Gallocatechin-(4-alpha-8)-epigallocatechin Plant
Gamma-terpinene Plant
Gamma-terpineol Plant
Glaucine Leaf
Hardwickic-acid Plant
Isoboldine Plant
Korberin-a Plant
Korberin-b Plant
Lignans Plant
Lignin Plant
Linalol Plant
Magnoflorine Plant
Methyl-thymol Plant
Myrcene Plant
Norisoboldine Plant
P-cymene Plant
Phenols Plant
Proanthocyanidins Latex Exudate 900,000
Procyanidin Latex Exudate
Procyanidin-b-1 Plant
Procyanidin-b-4 Plant
Prodelphinidin Latex Exudate
Resin Plant
Sinoacutine Leaf 1
Sitosterol Latex Exudate
Sitosterol-beta-glucopyranoside Latex Exudate
Tannin Plant
Taspine Latex Exudate 13,000 204,000
Terpinen-4-ol Plant
Thaliporphine Leaf
Vanillin Plant
Reference: Dr. Duke's Phytochemical and Ethnobotanical Databases. [Online Database]