Apocynum cannabinum Health effects and herbal facts

Known as
American-hemp dogbane hemp dogbane Indian-hemp

Apocynum cannabinum is a perennial herbaceous plant that grows throughout much of North America - in the southern half of Canada and throughout the United States. It is a poisonous plant: Apocynum means "poisonous to dogs". All parts of the plant are poisonous and can cause cardiac arrest if ingested. The cannabinum in the scientific name and the common names Hemp Dogbane and Indian Hemp refer to its similarity to Cannabis as a fiber plant, rather than as a source of a psychoactive drug Although dogbane is poisonous to livestock, it likely got its name from its resemblance to a European species of the same name.

Apocynum cannabinum

Medical use

Economic importance of Apocynum cannabinum

Medicines folklore
Vertebrate poisons mamals

Gallery

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Geografical distribution

  • ASIA-TEMPERATE
    Cultivated
    • Eastern Asia: Korea
  • NORTHERN AMERICA
    Native
    • Subarctic America: Canada - Northwest Territory
    • Eastern Canada: Canada - New Brunswick, Newfoundland, Nova Scotia, Ontario, Quebec
    • Western Canada: Canada - Alberta, British Columbia, Manitoba, Saskatchewan
    • Northeastern U.S.A.: United States - Connecticut, Indiana, Maine, Massachusetts, Michigan, New Hampshire, New Jersey, New York, Ohio, Pennsylvania, Rhode Island, Vermont, West Virginia
    • North-Central U.S.A.: United States - Illinois, Iowa, Kansas, Minnesota, Missouri, Nebraska, North Dakota, Oklahoma, South Dakota, Wisconsin
    • Northwestern U.S.A.: United States - Colorado, Idaho, Montana, Oregon, Washington, Wyoming
    • Southeastern U.S.A.: United States - Alabama, Arkansas, Delaware, District of Columbia, Florida, Georgia, Kentucky, Louisiana, Maryland, Mississippi, North Carolina, South Carolina, Tennessee, Virginia
    • South-Central U.S.A.: United States - New Mexico, Texas
    • Southwestern U.S.A.: United States - Arizona, California, Nevada, Utah
    • Northern Mexico: Mexico - Baja Norte, Chihuahua, Coahuila, Nuevo Leon, Tamaulipas
    • Southern Mexico: Mexico - Queretaro

Biological activities

Abortifacient
Oleanolic-acid found in Root
Analgesic
Alpha-amyrin found in Root
Anthelmintic
Tannin found in Plant
AntiEBV
Lupeol found in Root
AntiHIV
Oleanolic-acid found in Root
Tannin found in Plant
AntiPGE2
Oleanolic-acid found in Root
AntiTGF-beta
Oleanolic-acid found in Root
Antiallergic
Oleanolic-acid found in Root
Antiangiogenic
Lupeol found in Root
Antiarrhythmic
Oleanolic-acid found in Root
Antiatherosclerotic
Oleanolic-acid found in Root
Antibacterial
Harmalol found in Root
Oleanolic-acid found in Root
Tannin found in Plant
Anticancer
Tannin found in Plant
Anticarcinomic
Apocannoside found in Root
Cymarin found in Root
Oleanolic-acid found in Root
Anticariogenic
Oleanolic-acid found in Root
Tannin found in Plant
Anticomplement
Oleanolic-acid found in Root
Antidiarrheic
Tannin found in Plant
Antidysenteric
Tannin found in Plant
Antiedemic
Alpha-amyrin found in Root
Lupeol found in Root
Oleanolic-acid found in Root
Antifertility
Oleanolic-acid found in Root
Antiflu
Lupeol found in Root
Antigingivitic
Oleanolic-acid found in Root
Antihepatotoxic
Oleanolic-acid found in Root
Tannin found in Plant
Antihyperglycemic
Lupeol found in Root
Antihyperlipidemic
Oleanolic-acid found in Root
Antihypertensive
Tannin found in Plant
Antiinflammatory
Alpha-amyrin found in Root
Lupeol found in Root
Oleanolic-acid found in Root
Antiischemic
Oleanolic-acid found in Root
Antileukemic
Oleanolic-acid found in Root
Antileukotriene
Oleanolic-acid found in Root
Antilipolytic
Tannin found in Plant
Antimitotic
Harmalol found in Root
Antimutagenic
Tannin found in Plant
Antinephritic
Oleanolic-acid found in Root
Tannin found in Plant
Antinociceptive
Alpha-amyrin found in Root
Antiophidic
Tannin found in Plant
Antioxalate
Lupeol found in Root
Antioxidant
Lupeol found in Root
Oleanolic-acid found in Root
Tannin found in Plant
Antiperiodontic
Oleanolic-acid found in Root
Antiperoxidant
Lupeol found in Root
Oleanolic-acid found in Root
Antiplaque
Oleanolic-acid found in Root
Antiplasmodial
Oleanolic-acid found in Root
Antiprostaglandin
Lupeol found in Root
Antiradicular
Tannin found in Plant
Antirenitic
Tannin found in Plant
Antirheumatic
Lupeol found in Root
Antisarcomic
Oleanolic-acid found in Root
Antiseptic
Oleanolic-acid found in Root
Antitumor-Promoter
Tannin found in Plant
Antitumor
Alpha-amyrin found in Root
Apocannoside found in Root
Lupeol found in Root
Oleanolic-acid found in Root
Tannin found in Plant
Antiulcer
Alpha-amyrin found in Root
Oleanolic-acid found in Root
Tannin found in Plant
Antiurethrotic
Lupeol found in Root
Antiviral
Lupeol found in Root
Oleanolic-acid found in Root
Tannin found in Plant
Aphrodisiac
Harmalol found in Root
Aromatase-Inhibitor
Oleanolic-acid found in Root
Beta-Blocker
Oleanolic-acid found in Root
Beta-Glucuronidase-Inhibitor
Oleanolic-acid found in Root
CNS-Stimulant
Harmalol found in Root
COX-2-Inhibitor
Oleanolic-acid found in Root
Cancer-Preventive
Oleanolic-acid found in Root
Tannin found in Plant
Carcinogenic
Tannin found in Plant
Cardiac
Apocannoside found in Root
Cymarol found in Plant
Cardioprotective
Oleanolic-acid found in Root
Cardiotonic
Cymarin found in Root
Oleanolic-acid found in Root
Chelator
Tannin found in Plant
Cyclooxygenase-Inhibitor
Oleanolic-acid found in Root
Tannin found in Plant
Cytotoxic
Alpha-amyrin found in Root
Harmalol found in Root
Lupeol found in Root
Desmutagenic
Harmalol found in Root
Diuretic
Oleanolic-acid found in Root
Elastase-Inhibitor
Oleanolic-acid found in Root
FPTase-Inhibitor
Lupeol found in Root
Gastroprotective
Alpha-amyrin found in Root
Glucosyl-Transferase-Inhibitor
Tannin found in Plant
Hepatoprotective
Alpha-amyrin found in Root
Oleanolic-acid found in Root
Tannin found in Plant
Hypolipemic
Oleanolic-acid found in Root
Hypotensive
Lupeol found in Root
Oleanolic-acid found in Root
Immunomodulator
Oleanolic-acid found in Root
Immunosuppressant
Tannin found in Plant
Insectifuge
Alpha-amyrin found in Root
Leucocytogenic
Oleanolic-acid found in Root
Lipoxygenase-Inhibitor
Tannin found in Plant
MAO-Inhibitor
Tannin found in Plant
Myocardiotonic
Cymarin found in Root
Myotonic
Cymarin found in Root
NF-kB-Inhibitor
Oleanolic-acid found in Root
Ornithine-Decarboxylase-Inhibitor
Tannin found in Plant
Pesticide
Cymarin found in Root
Harmalol found in Root
Lupeol found in Root
Tannin found in Plant
Phagocytotic
Oleanolic-acid found in Root
Piscicide
Oleanolic-acid found in Root
Prostaglandin-Synthesis-Inhibitor
Oleanolic-acid found in Root
Psychotropic
Tannin found in Plant
Sedative
Oleanolic-acid found in Root
TOPO-2-Inhibitor
Lupeol found in Root
Uterotonic
Oleanolic-acid found in Root
Vasodilator
Cymarin found in Root
Vasopressor
Oleanolic-acid found in Root
Xanthine-Oxidase-Inhibitor
Tannin found in Plant

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Chemicals detected

Chemical Plant part Low ppm High ppm
Alpha-amyrin Root
Androsterol Root
Apocannoside Root
Cannogenin Root
Cymarin Root
Cymarol Plant
Cynocannoside Root
Fat Seed 226,000 238,000
Harmalol Root
Homoandrosterol Root
K-strophanthin Root
Lupeol Root
Oleanolic-acid Root
P-oxyacetophenone Root
Protein Seed 287,000 331,000
Resin Plant
Strophanthin-cymaroside Plant
Tannin Plant
Reference: Dr. Duke's Phytochemical and Ethnobotanical Databases. [Online Database]